07748
Gabapentin
pharmaceutical secondary standard; traceable to USP
Synonym(s):
1-(Aminomethyl)-cyclohexaneacetic acid, Neurontin
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About This Item
Empirical Formula (Hill Notation):
C9H17NO2
CAS Number:
Molecular Weight:
171.24
EC Number:
262-076-3
UNSPSC Code:
41116000
MDL number:
Beilstein/REAXYS Number:
2359739
InChI key
UGJMXCAKCUNAIE-UHFFFAOYSA-N
InChI
1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)
SMILES string
NCC1(CC(O)=O)CCCCC1
agency
traceable to USP 1287303
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Mark P Jensen et al.
The Clinical journal of pain, 29(9), 770-774 (2013-02-02)
This study evaluated the long-term safety and tolerability of a gastroretentive formulation of gabapentin (G-GR) and its effect on weight gain in postherpetic neuralgia (PHN) patients participating in a 14-week, open-label extension to a 10-week double-blind study. Patients with PHN
Bernd Saletu et al.
Psychiatria Danubina, 25(4), 426-434 (2013-11-20)
The past two decades have witnessed substantial progress in methodology and knowledge in sleep research all over the world. The paper at hand will present some recent local contributions to this field. The first is a European project (SIESTA) focusing
Richard Rauck et al.
Anesthesiology, 119(3), 675-686 (2013-07-10)
Oral gabapentin is approved as an anticonvulsant medication and to treat postherpetic neuralgia. Its nonopioid properties and presumed spinal site of analgesic action made the study on intrathecal gabapentin attractive to establish the minimum effective dose for a later, pivotal
Carlos C Câmara et al.
Neuroscience letters, 556, 93-98 (2013-10-22)
Gabapentin (GBP) is an anti-convulsive drug often used as analgesic to control neuropathic pain. This study aimed at evaluating whether oral GBP treatment could improve nerve inflammation response after sciatic nerve constriction in association with selected pain and motor spontaneous
Barbara J Mason et al.
JAMA internal medicine, 174(1), 70-77 (2013-11-06)
Approved medications for alcohol dependence are prescribed for less than 9% of US alcoholics. To determine if gabapentin, a widely prescribed generic calcium channel/γ-aminobutyric acid-modulating medication, increases rates of sustained abstinence and no heavy drinking and decreases alcohol-related insomnia, dysphoria
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