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07964

Methoxypolyethylene glycol amine

Name: Methoxypolyethylene glycol amine
Brand: SIAL

750 MW

Synonym(s):

mPEG-NH₂, O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine

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About This Item

Linear Formula:

H₂NCH₂CH₂(OCH₂CH₂)_nOCH₃

CAS Number:

80506-64-5

NACRES:

NA.22

UNSPSC Code:

12162002

MDL number:

MFCD00131599

Form:

solid

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Properties

Quality Segment

100

form

solid

color

white to yellow

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

Description

Application

Methoxypolyethylene glycol amine can:

Form dendritic micelles to enhance the solubility of hydrophobic compounds.
Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.

Other Notes

Oligomer used to prepare PEG-ylated conjugates having the advantage of reduced immunogenicity and increased serum half life

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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