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Merck
CN

08088

p-Aminohippuric acid

puriss., ≥99.0% (T)

Synonym(s):

4-Aminohippuric acid, N-(4-Aminobenzoyl)glycine

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About This Item

Linear Formula:
NH2C6H4C(O)NHCH2COOH
CAS Number:
Molecular Weight:
194.19
EC Number:
200-518-9
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1213676
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InChI

1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13)

InChI key

HSMNQINEKMPTIC-UHFFFAOYSA-N

SMILES string

Nc1ccc(cc1)C(=O)NCC(O)=O

grade

puriss.

assay

≥99.0% (T)

mp

199-200 °C (dec.) (lit.), 200-202 °C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Alberto Montanari et al.
American journal of physiology. Renal physiology, 303(5), F648-F658 (2012-06-29)
According to the "tubulocentric" hypothesis of the glomerular hyperfiltration of diabetes mellitus (DM), tubuloglomerular feedback (TGF) is the critical determinant of the related renal hemodynamic dysfunction. To examine the role of TGF in human type 1 DM, 12 salt-replete healthy
Maria V Irazabal et al.
Kidney international, 80(3), 295-301 (2011-05-06)
Tolvaptan and related V(2)-specific vasopressin receptor antagonists have been shown to delay disease progression in animal models of polycystic kidney disease. Slight elevations in serum creatinine, rapidly reversible after drug cessation, have been found in clinical trials involving tolvaptan. Here
Justin Koteff et al.
British journal of clinical pharmacology, 75(4), 990-996 (2012-08-22)
Dolutegravir (DTG; S/GSK1349572) is under clinical development as a once daily, unboosted integrase inhibitor for the treatment of HIV infection. The effect of DTG on glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and creatinine clearance (CLcr ) was
K D Gunston et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 54(12), 499-500 (1978-09-16)
A close correlation was found between amniotic fluid volume measured by using para-aminohippuric acid and the clinical assessment of volume. No correlation was found between measured amniotic fluid volume and fetal weight, length, or weight for gestational age.
A Edlund et al.
Clinical science (London, England : 1979), 87(2), 143-149 (1994-08-01)
1. The effects of local intra-arterial infusion of adenosine on renal blood flow, glomerular filtration and renin release in eight healthy awake subjects have been examined. 2. Renal blood flow and glomerular filtration rate were measured as the clearances of

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