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08088

p-Aminohippuric acid

Name: <I>p</I>-Aminohippuric acid
Brand: SIAL

puriss., ≥99.0% (T)

Synonym(s):

4-Aminohippuric acid, N-(4-Aminobenzoyl)glycine

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About This Item

Linear Formula:

NH₂C₆H₄C(O)NHCH₂COOH

CAS Number:

61-78-9

Molecular Weight:

194.19

EC Number:

200-518-9

UNSPSC Code:

12352200

MDL number:

MFCD00007890

Beilstein/REAXYS Number:

1213676

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Properties

grade

puriss.

assay

≥99.0% (T)

mp

199-200 °C (dec.) (lit.), 200-202 °C

SMILES string

Nc1ccc(cc1)C(=O)NCC(O)=O

InChI

1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13)

InChI key

HSMNQINEKMPTIC-UHFFFAOYSA-N

Description

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Renal hemodynamic response to L-arginine in uncomplicated, type 1 diabetes mellitus: the role of buffering anions and tubuloglomerular feedback.

Alberto Montanari et al.

American journal of physiology. Renal physiology, 303(5), F648-F658 (2012-06-29)

According to the "tubulocentric" hypothesis of the glomerular hyperfiltration of diabetes mellitus (DM), tubuloglomerular feedback (TGF) is the critical determinant of the related renal hemodynamic dysfunction. To examine the role of TGF in human type 1 DM, 12 salt-replete healthy

Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease.

Maria V Irazabal et al.

Kidney international, 80(3), 295-301 (2011-05-06)

Tolvaptan and related V(2)-specific vasopressin receptor antagonists have been shown to delay disease progression in animal models of polycystic kidney disease. Slight elevations in serum creatinine, rapidly reversible after drug cessation, have been found in clinical trials involving tolvaptan. Here

A phase 1 study to evaluate the effect of dolutegravir on renal function via measurement of iohexol and para-aminohippurate clearance in healthy subjects.

Justin Koteff et al.

British journal of clinical pharmacology, 75(4), 990-996 (2012-08-22)

Dolutegravir (DTG; S/GSK1349572) is under clinical development as a once daily, unboosted integrase inhibitor for the treatment of HIV infection. The effect of DTG on glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and creatinine clearance (CLcr ) was

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Global Trade Item Number

SKU	GTIN
126411-5G	04061838724144