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Merck
CN

08751

4-Amino-3-hydroxy-1-naphthalenesulfonic acid

for spectrophotometric det. of Si, ≥90.0% (CHN)

Synonym(s):

1-Amino-2-naphthol-4-sulfonic acid

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About This Item

Linear Formula:
H2NC10H5(OH)SO3H
CAS Number:
116-63-2
Molecular Weight:
239.25
UNSPSC Code:
41116105
NACRES:
NA.21
PubChem Substance ID:
329748632
EC Number:
204-147-3
Beilstein/REAXYS Number:
2697469
MDL number:
MFCD00004019

Key Documents

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Product Name

4-Amino-3-hydroxy-1-naphthalenesulfonic acid, for spectrophotometric det. of Si, ≥90.0% (CHN)

InChI key

RXCMFQDTWCCLBL-UHFFFAOYSA-N

InChI

1S/C10H9NO4S/c11-10-7-4-2-1-3-6(7)9(5-8(10)12)16(13,14)15/h1-5,12H,11H2,(H,13,14,15)

SMILES string

Nc1c(O)cc(c2ccccc12)S(O)(=O)=O

assay

≥90.0% (CHN)

form

powder

quality

for spectrophotometric det. of Si

technique(s)

UV/Vis spectroscopy: suitable

mp

290 °C (dec.) (lit.)

Quality Level

100

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Application

4-Amino-3-hydroxy-1-naphthalenesulfonic acid has been used to study separation of aromatic sulfonated compounds using Ion-interaction high-performance liquid chromatography and micellar electrokinetic capillary chromatography techniques. It has also been used as a starting material which when reacted with palmitoyl chloride yields the following derivatives:
  • 2′-Pentadecylnaphth[3,4-d]oxazole-1-sulfonic acid
  • 4-Amino-3-(palmitoyloxy)-1-naphthalenesufonic acid
  • 4-(Palmitoylamino)-3-hydroxy-1-naphthalenesulfonic acid
  • 4-(Palmitoylamino)-3-(palmitoyloxy)-1-naphthalenesulfonic acid

General description

4-Amino-3-hydroxy-1-naphthalenesulfonic acid is an aromatic amino-sulfonic acid.

Other Notes

Reagent for the spectrophotometric det. of silicon

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7088
BCCM2883
BCCH5207
BCCF6026
BCCC3655

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Synthesis of naphthalenesulfonic acid small molecules as selective inhibitors of the DNA polymerase and ribonuclease H activities of HIV-1 reverse transcriptase.
Mohan P
Journal of Medicinal Chemistry, 37(16), 2513-2519 (1994)
F.A. Sorrentino et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 15, 441-441 (1970)
Ion-interaction high-performance liquid chromatography and micellar electrokinetic capillary chromatography: two complementary techniques for the separation of aromatic sulfonated compounds.
Angelino, S., et al.
Journal of Chromatography A, 845.1, 257-271 (1999)

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