09656
1-Hydroxybenzotriazole polymer-bound
100-300 mesh, extent of labeling: ~1.0 mmol/g loading, matrix polystyrene, crosslinked with 2% DVB
Synonym(s):
1-Hydroxybenzotriazole-6-carboxamide bound to polystyrene crosslinked with DVB, HOBt polymer-bound
reaction suitability
reaction type: solution phase peptide synthesis
extent of labeling
~1.0 mmol/g loading
matrix
polystyrene, crosslinked with 2% DVB
particle size
100-300 mesh
Quality Level
Other Notes
Polymer bound HOBt for the synthesis of amides and peptides with carbodiimides and other activating reagent without racemization
Hazard Classifications
Flam. Sol. 1
signalword
Danger
hcodes
pcodes
Storage Class
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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Iuliana E. Pop et al.
The Journal of organic chemistry, 62(8), 2594-2603 (1997-04-18)
The synthesis of a new polymer-supported coupling reagent derived from 1-hydroxybenzotriazole is described. An aminomethylated polystyrene was functionalized by reaction with 3-nitro-4-chlorobenzenesulfonyl chloride (2) followed by treatement with hydrazine hydrate, to give the polymeric N-benzyl-1-hydroxybenzotriazole-6-sulfonamide (4).The polymeric reagent 4 was
K. Dendrinos et al.
Chemical Communications (Cambridge, England), 499-499 (1998)
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