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1048

Sigma-Aldrich

4-Nitrophenol

spectrophotometric grade

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Synonym(s):
p-Nitrophenol
Linear Formula:
O2NC6H4OH
CAS Number:
Molecular Weight:
139.11
Beilstein:
1281877
EC Number:
MDL number:
eCl@ss:
39032018
PubChem Substance ID:
NACRES:
NA.21

grade

spectrophotometric grade

Quality Level

vapor pressure

0.6 mmHg ( 120 °C)

form

powder

autoignition temp.

541 °F

technique(s)

UV/Vis spectroscopy: suitable

bp

279 °C (lit.)

mp

110-115 °C (lit.)

solubility

ethanol: 95%, clear, dark yellow (100 mg/mL)

SMILES string

O=N(C1=CC=C(O)C=C1)=O

InChI

1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H

InChI key

BTJIUGUIPKRLHP-UHFFFAOYSA-N

Gene Information

human ... UGT1A4(54657)

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Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 - STOT RE 2 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

336.2 °F

Flash Point(C)

169 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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A Mitrofanova et al.
Nature communications, 10(1), 2692-2692 (2019-06-21)
Sphingomyelin phosphodiesterase acid-like 3b (SMPDL3b) is a lipid raft enzyme that regulates plasma membrane (PM) fluidity. Here we report that SMPDL3b excess, as observed in podocytes in diabetic kidney disease (DKD), impairs insulin receptor isoform B-dependent pro-survival insulin signaling by
Siew Hong Lam et al.
Biochimica et biophysica acta, 1830(10), 4778-4789 (2013-06-25)
4-Nitrophenol (4-NP) is a prioritized environmental pollutant and its toxicity has been investigated using zebrafish, advocated as an alternative toxicological model. However, molecular information of 4-NP induced hepatotoxicity is still limited. This study aimed to obtain molecular insights into 4-NP-induced
Ali Mehdinia et al.
Journal of chromatography. A, 1283, 82-88 (2013-03-08)
In this study, an analytical procedure for the selective extraction and detection of 4-nitrophenol (4-NP) was investigated by using of molecularly imprinted polymer on the surface of magnetic nanoparticles (MNPs). The magnetic nanoparticles were modified by tetraethyl orthosilicate (TEOS) and
Ipsita K Sen et al.
Carbohydrate polymers, 91(2), 518-528 (2012-11-06)
Gold nanoparticles were synthesized by reducing chloroauric acid with a glucan, isolated from an edible mushroom Pleurotus florida, cultivar Assam Florida. Here, glucan acts as reducing as well as stabilizing agent. The synthesized gold nanoparticles were characterized by UV-visible spectroscopy
Alex V Birk et al.
The Journal of laboratory and clinical medicine, 140(3), 166-175 (2002-09-25)
Extracellular adenosine triphosphate (ATP) regulates platelet reactivity by way of direct action on platelet purinergic receptors or by hydrolysis to adenosine diphosphate (ADP). Subsequent metabolism of ATP and ADP to adenosine monophosphate (AMP) and adenosine inhibits platelet aggregation. Endothelial cell

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