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Merck
CN

10784

Sigma-Aldrich

Antipyrine

tested according to Ph. Eur.

Synonym(s):

Phenazonum, 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one, Phenazone

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About This Item

Empirical Formula (Hill Notation):
C11H12N2O
CAS Number:
60-80-0
Molecular Weight:
188.23
Beilstein:
157775
EC Number:
200-486-6
MDL number:
MFCD00003146
UNSPSC Code:
41116107
PubChem Substance ID:
329749157
NACRES:
NA.21

Key Documents

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Agency

USP/NF
tested according to Ph. Eur.

Quality Level

100

form

crystals and lumps
powder

mp

109-111 °C (lit.)

solubility

H2O: soluble 1 gm in less than 1ml
alcohol: soluble 1 gm in 1.3 ml
chloroform: soluble 1 gm in 1 ml
diethyl ether: soluble 1 gm in 43 ml

application(s)

pharmaceutical (small molecule)

SMILES string

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChI key

VEQOALNAAJBPNY-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742)

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Application

Antipyrine has been used for immunoblotting. It has also been used as an internal reference marker for studying the transport characteristics of platinum-containing drug, cisplatin in the human placenta in vitro.

Biochem/physiol Actions

Antipyrine also referred to as phenazone or phenazonum is an anti-inflammatory agent that possesses analgesic, antipyretic and platelet-inhibitory actions.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH7205
BCCG5616
BCCG0014
BCCD7833
BCCC8539

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