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Zeaxanthin

analytical standard

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Synonym(s):
β,β-Carotene-3,3′-diol
Empirical Formula (Hill Notation):
C40H56O2
CAS Number:
Molecular Weight:
568.87
EC Number:
MDL number:
PubChem Substance ID:
E Number:
161h
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C)\C=C\C=C(C)\C=C\C2=C(C)C[C@@H](O)CC2(C)C

InChI

1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-24,35-36,41-42H,25-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36-/m1/s1

InChI key

JKQXZKUSFCKOGQ-QAYBQHTQSA-N

General description

Zeaxanthin is a carotenoid that belongs to the group of xanthophylls. A dihydroxy derivative of β-carotene, it is found in vegetables and fruits, besides the eyes and skin of humans. It is known to show anti-oxidant, anti-inflammatory, anti-apoptotic, and neuroprotective properties.

Application

The analytical standards can also be used as follows:

  • Optimization of an ultrasonic-assisted extraction procedure for obtaining zeaxanthin and lutein from corn gluten meal samples for their determination by high-performance liquid chromatography-UV-Visible detection
  • Simultaneous quantification of five carotenoids and two chlorophylls from soybean flour samples by reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with UV-Vis detector
  • Multi-residue analysis of carotenoids and apocarotenoids in intact human blood samples by supercritical fluid extraction and supercritical fluid chromatography-atmospheric pressure chemical ionization-triple quadrupole mass spectrometry detection (SFE-SFC-APCI/QqQ/MS)
  • High-performance liquid chromatography-diode array detector (HPLC-DAD) method-based determination of carotenoids in marigold flower and food supplement samples
  • Profiling of carotenoids and their isomers in different plant tissue samples by high-performance liquid chromatography (HPLC) using a C30 column and photodiode array (PDA) detection

Biochem/physiol Actions

Carotenoid pigment that contributes to the color of paprika. Zeaxanthin accumulates within the eye retina and is thought to decrease the incidence of macular degeneration.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Fenghua Chai et al.
Microbial cell factories, 16(1), 54-54 (2017-03-31)
Due to excellent performance in antitumor, antioxidation, antihypertension, antiatherosclerotic and antidepressant activities, crocetin, naturally exists in Crocus sativus L., has great potential applications in medical and food fields. Microbial production of crocetin has received increasing concern in recent years. However
Norman I Krinsky et al.
Annual review of nutrition, 23, 171-201 (2003-03-11)
The macular region of the primate retina is yellow in color due to the presence of the macular pigment, composed of two dietary xanthophylls, lutein and zeaxanthin, and another xanthophyll, meso-zeaxanthin. The latter is presumably formed from either lutein or
Chikara Kaito et al.
PLoS pathogens, 16(4), e1008469-e1008469 (2020-04-24)
The molecular mechanisms that allow pathogenic bacteria to infect animals have been intensively studied. On the other hand, the molecular mechanisms by which bacteria acquire virulence functions are not fully understood. In the present study, we experimentally evaluated the evolution
S Anna Ceravolo et al.
Molecular nutrition & food research, 63(15), e1801051-e1801051 (2019-04-06)
Steady-state visual evoked potentials (SSVEP) can be used to test the topological response of cortical neurons. Studies have shown that a lutein (L) preferentially accumulates within cortical tissue. L, zeaxanthin (Z), and their isomers can be measured directly in retina
Caitlyn G Edwards et al.
Molecular nutrition & food research, 63(15), e1801059-e1801059 (2019-03-01)
Macular accumulation of xanthophyll carotenoids (lutein, zeaxanthin) is known to have neuroprotective potential, yet their influence on cognition among overweight adults and those with obesity remains limited. This study examines the impact of macular xanthophylls on attentional resource allocation and

Articles

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Protocols

HPLC Analysis of Carotene Compounds on Ascentis® RP-Amide

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