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Merck
CN

15236

N,O-Bis(trimethylsilyl)carbamate

≥98.0% (T)

Synonym(s):

BSC, Trimethylsilyl N-(trimethylsilyl)carbamate

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About This Item

Linear Formula:
(CH3)3SiNHCO2Si(CH3)3
CAS Number:
Molecular Weight:
205.40
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
252-520-4
Beilstein/REAXYS Number:
2043399
MDL number:
Assay:
≥98.0% (T)
Form:
solid
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InChI key

DGIJAZGPLFOQJE-UHFFFAOYSA-N

InChI

1S/C7H19NO2Si2/c1-11(2,3)8-7(9)10-12(4,5)6/h1-6H3,(H,8,9)

SMILES string

C[Si](C)(C)NC(=O)O[Si](C)(C)C

assay

≥98.0% (T)

form

solid

mp

77-83 °C

functional group

amine

Quality Level

Related Categories

Other Notes

Extremely suitable reagent for the silylation of alcohols, phenols and carboxylic acids. The only by-products are CO2 and NH3; Silyloxycarbonylation of amines; Acylisocyanates from carboxylic acid chlorides

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Abi Vijenthira et al.
Blood, 136(25), 2881-2892 (2020-10-29)
Outcomes for patients with hematologic malignancy infected with COVID-19 have not been aggregated. The objective of this study was to perform a systematic review and meta-analysis to estimate the risk of death and other important outcomes for these patients. We
Zhur. Obshch. Khim., 50, 955-955 (1980)
Barbara Melosky et al.
The oncologist, 25(1), 64-77 (2019-05-30)
Lung cancer is one of the most common types of cancer, resulting in approximately 1.8 million deaths worldwide. Immunotherapy using checkpoint inhibitors has become standard of care in advanced non-small cell lung cancer (NSCLC), and there is increasing interest in
V.P. Kozyukov et al.
Zhur. Obshch. Khim., 51, 239-239 (1981)
M J Sorich et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 26(1), 13-21 (2014-08-15)
Monoclonal antibodies (mAbs) targeting the epidermal growth factor receptor (EGFR) prolong survival in metastatic colorectal cancer (mCRC) Kirsten rat sarcoma viral oncogene (KRAS) exon 2 wild-type tumors. Recent evidence has suggested that other RAS mutations (in exons 3 and 4

Articles

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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