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Merck
CN

15236

N,O-Bis(trimethylsilyl)carbamate

≥98.0% (T)

Synonym(s):

BSC, Trimethylsilyl N-(trimethylsilyl)carbamate

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About This Item

Linear Formula:
(CH3)3SiNHCO2Si(CH3)3
CAS Number:
Molecular Weight:
205.40
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
252-520-4
Beilstein/REAXYS Number:
2043399
MDL number:
Assay:
≥98.0% (T)
Form:
solid
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Quality Level

assay

≥98.0% (T)

form

solid

mp

77-83 °C

functional group

amine

SMILES string

C[Si](C)(C)NC(=O)O[Si](C)(C)C

InChI

1S/C7H19NO2Si2/c1-11(2,3)8-7(9)10-12(4,5)6/h1-6H3,(H,8,9)

InChI key

DGIJAZGPLFOQJE-UHFFFAOYSA-N

Other Notes

Extremely suitable reagent for the silylation of alcohols, phenols and carboxylic acids. The only by-products are CO2 and NH3; Silyloxycarbonylation of amines; Acylisocyanates from carboxylic acid chlorides


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Articles

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs


Gregor Vlacic et al.
Cells, 8(9) (2019-09-19)
Malignant pleural mesothelioma (MPM) is a devastating malignancy with limited therapeutic options. Fibroblast growth factor receptors (FGFR) and their ligands were shown to contribute to MPM aggressiveness and it was suggested that subgroups of MPM patients could benefit from FGFR-targeted
Ronak Saluja et al.
Journal of oncology practice, 14(5), e280-e294 (2018-03-31)
The purpose of this study was to determine if clinical benefits of novel anticancer drugs, measured by the ASCO Value Framework and European Society of Medical Oncology (ESMO) Magnitude of Clinical Benefit Scale, have increased over time in parallel with
Stefania De Lorenzo et al.
Scientific reports, 8(1), 9997-9997 (2018-07-04)
There is a relative lack of evidence about systemic treatments in patients with hepatocellular carcinoma (HCC) and moderate liver dysfunction (Child-Pugh B). In this multicenter study we retrospectively analyzed data from Child-Pugh B-HCC patients naïve to systemic therapies, treated with



Global Trade Item Number

SKUGTIN
15236-10G04061832098241