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Merck
CN

156248

Sodium ethoxide

95%, powder

Synonym(s):

Sodium ethylate

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About This Item

Linear Formula:
CH3CH2ONa
CAS Number:
Molecular Weight:
68.05
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
3593646
Assay:
95%
Form:
powder
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Product Name

Sodium ethoxide, 95%

vapor density

1.6 (vs air)

Quality Level

vapor pressure

<0.1 mmHg ( 20 °C)

assay

95%

form

powder

SMILES string

[Na+].CC[O-]

InChI

1S/C2H5O.Na/c1-2-3;/h2H2,1H3;/q-1;+1

InChI key

QDRKDTQENPPHOJ-UHFFFAOYSA-N

General description

Sodium ethoxide (Sodium ethylate) is a sodium alkoxide. It has been synthesized by reacting sodium with ethanol. It undergoes decomposition in the presence of water to afford ethanol and sodium hydroxide. It is widely employed as a strong base in organic synthesis studies.

Application


  • Organic solvent fractionation in lignin depolymerization: A study focused on enhancing the monophenolic yield of lignin depolymerization using a dualistic aprotic solvent system, employing sodium ethoxide for effective organic solvent fractionation. This approach underscores the versatility of sodium ethoxide in complex organic synthesis and biomass processing (Xu et al., 2024).

  • Solid-state self-quenching-resistant sulfur dots: Research on sulfur dots utilized a solvent-type passivation strategy to control solid-state self-quenching-resistant behavior, where sodium ethoxide played a crucial role in the synthesis process. This study illustrates sodium ethoxides utility in advanced materials synthesis, particularly for optoelectronic applications (Wu et al., 2022).

  • Synthesis of corrosion inhibitors: Sodium ethoxide was used in the efficient synthesis of 6,7-Dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile compounds, demonstrating its applicability as a base in the synthesis of corrosion inhibitors for steel alloys. This application combines computational and practical approaches to highlight sodium ethoxide′s role in materials science and corrosion prevention (Abd El-Lateef et al., 2022).

  • Colon-targeted drug delivery systems: The design and synthesis of Thieno[2,3-b]pyridines-chitosan nanocomposites for colon targeting employed sodium ethoxide. This research showcases sodium ethoxides application in the preparation of targeted drug delivery systems, focusing on enhancing the efficacy and specificity of pharmaceutical treatments (Mansour et al., 2020).

  • Synthesis of antimicrobial compounds: Sodium ethoxide was integral in the synthesis of novel bis-alpha,beta-unsaturated ketones and nicotinonitrile derivatives, aimed at antimicrobial applications. This study highlights the compound′s critical role in the development of new antimicrobial agents, demonstrating its utility in medicinal chemistry (Altalbawy, 2013).



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Danger

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

flash_point_f

86.0 °F - closed cup

flash_point_c

30 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1A

supp_hazards

Regulatory Information

监管及禁止进口产品

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Charanjit S Sethi et al.
Investigative ophthalmology & visual science, 46(1), 329-342 (2004-12-30)
To investigate glial remodeling and neuronal plasticity in adult human retinal detachment complicated by proliferative vitreoretinopathy (PVR) and to grade pathologic changes with a severity scoring system. Sixteen full-thickness retinectomy specimens obtained at retinal relaxing surgery for PVR were fixed
Franklin R Tay et al.
Journal of endodontics, 31(8), 593-598 (2005-07-27)
Polycaprolactone, a thermoplastic aliphatic polyester, is reportedly susceptible to both alkaline and enzymatic hydrolyzes. This screening study examined the susceptibility of Resilon, a polycaprolactone-based root filling composite, to alkaline hydrolysis. There were 15-mm diameter disks of Resilon and Obtura gutta-percha
Zhao Cai et al.
Applied immunohistochemistry & molecular morphology : AIMM, 13(3), 292-294 (2005-08-06)
The authors describe a simple and cost-effective method of immunostaining semithin epoxy resin sections of peripheral nerve for light microscopy with antibodies to myelin protein zero, peripheral myelin protein 22, myelin basic protein, and neurofilament protein 200 using a combined



Global Trade Item Number

SKUGTIN
156248-500G04061838742544
156248-5G04061838742551
156248-100G04061838742537