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Merck
CN

16715

Thiamphenicol

analytical standard

Synonym(s):

D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide

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About This Item

Empirical Formula (Hill Notation):
C12H15Cl2NO5S
CAS Number:
Molecular Weight:
356.22
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
239-355-3
Beilstein/REAXYS Number:
2819542
MDL number:
eCl@ss:
25140904
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grade

analytical standard

Quality Segment

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

solubility

ethanol: 50 mg/mL, clear, colorless to faintly yellow

application(s)

clinical

format

neat

storage temp.

2-8°C

SMILES string

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl

InChI

1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1

InChI key

OTVAEFIXJLOWRX-NXEZZACHSA-N

General description

Thiamphenicol is an analog of a broad spectrum antibiotic, chloramphenicol. It shows therapeutic effects in respiratory infections, venereal diseases and bacterial prostatitis.
Chemical structure: sulfonamide

Application

Thiamphenicol may be used as a reference standard in the determination of thiamphenicol in honey using dispersive liquid-liquid microextraction (DLLME) coupled with high-performance liquid chromatography-variable wavelength detector (HPLC-VWD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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