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Sigma-Aldrich

1-Bromododecane

purum, ≥95.0% (GC)

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Synonym(s):
Dodecyl bromide, Lauryl bromide
Linear Formula:
CH3(CH2)11Br
CAS Number:
143-15-7
Molecular Weight:
249.23
Beilstein:
506159
EC Number:
205-587-9
MDL number:
MFCD00000225
PubChem Substance ID:
329751424
NACRES:
NA.22

vapor density

8.6 (vs air)

Quality Level

200

grade

purum

Assay

≥95.0% (GC)

form

liquid

refractive index

n20/D 1.458 (lit.)

bp

134-135 °C/6 mmHg (lit.)

mp

−11-−9 °C (lit.)

solubility

alcohol: soluble
diethyl ether: soluble
water: insoluble

density

1.038 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCCCCBr

InChI

1S/C12H25Br/c1-2-3-4-5-6-7-8-9-10-11-12-13/h2-12H2,1H3

InChI key

PBLNBZIONSLZBU-UHFFFAOYSA-N

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General description

1-Bromododecane is antimicrobial agent.

Application

1-Bromododecane was used in the synthesis of antimicrobial nanocomposite composed of reduced graphene oxide. It was used in the synthesis of quaternary ammonium chloride-modified poly(propylenimine) dendrimers. It was used as starting reagent in the synthesis of (-)-muricatacin.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315

Hazard Classifications

Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

230.0 °F

Flash Point(C)

110 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Jeong A Nam et al.
Acta biomaterialia, 9(8), 7996-8003 (2013-04-23)
We have prepared an antimicrobial nanocomposite composed of reduced graphene oxide (rGO) using antimicrobial agents and catechol derivative conjugated to polyethylene glycol-grafted poly(dimethylaminoethyl methacrylate) (PEG-g-PDMA). Graphene oxide (GO) has been simultaneously reduced by 2-chloro-3',4'-dihydroxyacetophenone (CCDP) in Tris buffer at pH
H Makabe et al.
Bioscience, biotechnology, and biochemistry, 57(6), 1028-1029 (1993-06-01)
The synthesis of (-)-muricatacin starting from 1-bromododecane and 2-pentyn-1-ol is described. 2-Pentadecyn-1-ol (4), which was prepared from 1-bromododecane (2) and 2-pentyn-1-ol (3), was converted to epoxy alcohol 6 through a two-step reaction sequence, 6 being successively submitted to tosylation, iodination
Eagambaram Murugan et al.
Langmuir : the ACS journal of surfaces and colloids, 20(19), 8307-8312 (2004-09-08)
Four different quaternary ammonium chloride-modified poly(propylenimine) (PPI) dendrimers were synthesized by alkylation of a PPI dendrimer having eight dimethylamino end groups with 1-bromooctane or 1-bromododecane. By varying the mole ratio of alkyl bromide to dendrimer, averages of 4-10 quaternary ammonium
Sung Ho Kim et al.
Biomaterials, 32(23), 5505-5514 (2011-05-03)
Water-soluble, thermoresponsive block copolymers based on a biodegradable platform were synthesized by the ring opening polymerization of cyclic carbonate monomers functionalized with hydrophilic and hydrophobic groups for application as nanocarriers in medicine. The approach based on cyclic carbonate monomers derived
N Konno et al.
Canadian journal of physiology and pharmacology, 69(11), 1705-1712 (1991-11-01)
Hydrogen peroxide (H2O2) and hypochlorite (HOCl) cause a variety of cellular dysfunctions. In this study we examined the effects of these agents on the electrical potential gradient across the inner membrane of mitochondria in situ in isolated rat heart myocytes.
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