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18189

2,4-Dinitrophenylhydrazine hydrochloric acid solution

Name: 2,4-Dinitrophenylhydrazine hydrochloric acid solution
Brand: SIAL

for TLC derivatization, ~0.005 M in ethanol

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About This Item

Empirical Formula (Hill Notation):

C₆H₆N₄O₄

CAS Number:

119-26-6

Molecular Weight:

198.14

UNSPSC Code:

41116105

NACRES:

NA.22

PubChem Substance ID:

329751648

MDL number:

MFCD00007578

Beilstein/REAXYS Number:

615586

Technique(s):

thin layer chromatography (TLC): suitable

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Properties

Quality Level

100

concentration

~0.005 M in ethanol

technique(s)

thin layer chromatography (TLC): suitable

refractive index

n20/D 1.374

density

0.843 g/mL at 20 °C

suitability

in accordance for application

storage temp.

2-8°C

SMILES string

NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2

InChI key

HORQAOAYAYGIBM-UHFFFAOYSA-N

Description

General description

2,4-Dinitrophenylhydrazine hydrochloric acid solution is a derivatization reagent.

Application

2,4-dinitrophenylhydrazine HCl solution was used in detecting Artemisinin derivatives usingf TLC silica gel sheets. It may be used in determination of carbonyl groups. It may also be used in a procedure for coating in situ silica gel with prepacked cartridges.

pictograms

GHS02,GHS05

signalword

Danger

hcodes

H225,H290,H319

pcodes

P210 - P233 - P234 - P240 - P241 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

57.2 °F

flash_point_c

14.0 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Evaluation of silica gel cartridges coated in situ with acidified 2,4-dinitrophenylhydrazine for sampling aldehydes and ketones in air.

S B Tejada

International journal of environmental analytical chemistry, 26(2), 167-185 (1986-01-01)

A procedure for coating in situ silica gel in prepacked cartridges with 2,4-dinitrophenylhydrazine (DNPH) acidified with hydrochloric acid is described. The coated cartridge was compared with a validated DNPH impinger method for sampling organic carbonyl compounds (aldehydes and ketones) in

Simple field assays to check quality of current artemisinin-based antimalarial combination formulations.

Jean-Robert Ioset et al.

PloS one, 4(9), e7270-e7270 (2009-10-01)

Malaria continues to be one of the major public health problems in Africa, Asia and Latin America. Artemisinin derivatives (ARTs; artesunate, artemether, and dihydroartemisinin) derived from the herb, Artemisia annua, are the most effective antimalarial drugs available providing rapid cures.

Micro method for determination of reactive carbonyl groups in proteins and peptides, using 2,4-dinitrophenylhydrazine.

R Fields et al.

The Biochemical journal, 121(4), 587-589 (1971-02-01)

A method is described for determining carbonyl groups that is especially suitable for use with proteins and peptides. It involves the determination of the extinction at 370nm of a sample solution after adding 2,4-dinitrophenylhydrazine. The reaction of 2,4-dinitrophenylhydrazine with pyruvoylglycine

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Global Trade Item Number

SKU	GTIN
18189-100ML-F	04061838755445