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18304

Sigma-Aldrich

Hydrogen peroxide solution

34.5-36.5%

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Synonym(s):
H2O2, Hydrogen Peroxide (H2O2)
Empirical Formula (Hill Notation):
H2O2
CAS Number:
7722-84-1
Molecular Weight:
34.01
Beilstein:
3587191
MDL number:
MFCD00011333
PubChem Substance ID:
57647730
NACRES:
NA.21

vapor pressure

23.3 mmHg ( 30 °C)

Quality Level

200

Assay

34.5-36.5%

shelf life

Shelf life is limited.

contains

stabilizer

reaction suitability

reagent type: oxidant

impurities

≤0.0002% heavy metals (as Pb)
≤0.02% free acid (as H2SO4)
≤0.05% non-volatile matter

ign. residue

≤0.03%

solubility

diethyl ether: soluble
petroleum ether: insoluble
water: soluble

density

1.130 g/cm3

storage temp.

2-8°C

SMILES string

OO

InChI

1S/H2O2/c1-2/h1-2H

InChI key

MHAJPDPJQMAIIY-UHFFFAOYSA-N

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Application

Hydrogen peroxide has been used for immunocytochemistry for eNOS. It has also been used for developing colour during detection of anti-prothrombin and anti-beta2-glycoprotein I antibodies. Additionally, it has also been used as a supplement in Hanks buffered saline solution for assessing the functional activity of myeloperoxidase.

Biochem/physiol Actions

Hydrogen peroxide (H2O2) is a strong oxidizer that can induce neuronal death in cultured cortical neurons via an apoptotic pathway. Oxidative burst facilitated by hydrogen peroxide is a key mechanism of plant defense during an incompatible interaction. Hydrogen peroxide injected in transgenic rice induces cell death as well as increase resistance to both bacterial and fungal pathogens.

Caution

keep in dark area

Other Notes

The article number 18304-4X5L will be discontinued. Please order the single bottle 18304-5L which is physically identical with the same exact specifications.
The article number 18304-6X1L will be discontinued. Please order the single bottle 18304-1L which is physically identical with the same exact specifications.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
易制爆化学品

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E R Whittemore et al.
Neuroscience, 67(4), 921-932 (1995-08-01)
A variety of neurodegenerative disease states have been associated with oxidative damage or stress. Such stress is thought to be mediated by excessive exposure of cells to reactive oxygen species such as free radicals, which can be generated following cell
R J Falk et al.
Clinical and experimental immunology, 89(2), 274-278 (1992-08-01)
We wondered whether anti-myeloperoxidase (MPO) autoantibodies (MPO-ANCA) found in patients with systemic vasculitis react with a conformational epitope or epitopes on the MPO molecule. Sera from 15 human MPO-ANCA, and a polyclonal and a monoclonal anti-MPO antibodies were reacted with
Aardra Kachroo et al.
Transgenic research, 12(5), 577-586 (2003-11-07)
Oxidative burst, mediated by hydrogen peroxide (H2O2), has been recognized as a key component of plant defense response during an incompatible interaction. To determine if elevated levels of H2O2 lead to cell death, activation of defense genes and enhanced resistance
F J Muñoz-Rodríguez et al.
Haematologica, 85(6), 632-637 (2000-06-28)
Antibodies to prothrombin (aII) have been identified in patients with antiphospholipid antibodies, but their clinical significance is not well known. The aim of our study was to investigate their prevalence and association with clinical manifestations of the antiphospholipid syndrome (APS)
J F Telfer et al.
Molecular human reproduction, 3(1), 69-75 (1997-01-01)
Immunocytochemistry was used to localize endothelial (eNOS) and inducible (iNOS) nitric oxide synthase in human uterine tissues collected at various stages of the menstrual cycle, after exposure to exogenous progestagens, and in early pregnancy. Endothelial NOS-like immunoreactivity was detected in
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