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Merck
CN

19448

Anhydroerythromycin A

analytical standard

Synonym(s):

Erythromycin anhydride

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About This Item

Empirical Formula (Hill Notation):
C37H65NO12
CAS Number:
23893-13-2
Molecular Weight:
715.91
NACRES:
NA.24
UNSPSC Code:
41116107

Key Documents

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Product Name

Anhydroerythromycin A, analytical standard

InChI

1S/C37H65NO12/c1-14-25-36(10)29(40)22(6)37(50-36)18(2)16-35(9,49-37)31(48-33-27(39)24(38(11)12)15-19(3)44-33)20(4)28(21(5)32(42)46-25)47-26-17-34(8,43-13)30(41)23(7)45-26/h18-31,33,39-41H,14-17H2,1-13H3/t18-,19-,20+,21-,22-,23+,24+,25-,26+,27-,28+,29-,30+,31-,33+,34-,35-,36-,37+/m1/s1

InChI key

YKAVHPRGGAUFDN-JTQLBUQXSA-N

SMILES string

CC[C@H]1OC(=O)[C@H](C)[C@@H](OC2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@]4(C)C[C@@H](C)C5(O4)OC1(C)[C@H](O)[C@H]5C

grade

analytical standard

assay

≥95.0% (TLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

mode of action

protein synthesis | interferes

storage temp.

−20°C

Quality Level

100

Related Categories

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Anhydroerythromycin A also known as erythromycin anhydride is a macrolide antibiotic, which are basic and lipophilic molecule.
Chemical structure: macrolide

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5359
BCCL4792
BCCK6161
BCCK1428
BCCG4428

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Shinwoo Yang et al.
Analytical and bioanalytical chemistry, 385(3), 623-636 (2006-05-23)
Two wastewater treatment plants (WWTPs) of northern Colorado were monitored for anhydroerythromycin and tylosin. An analytical method has been developed and validated for the trace determination and confirmation of these compounds in the raw influent and final effluent water matrices.
Norihide Nakada et al.
Water research, 41(19), 4373-4382 (2007-07-17)
We investigated the efficiencies of removal of 24 pharmaceutically active compounds (PhACs) during sand filtration and ozonation in an operating municipal sewage treatment plant (STP). The target compounds were 2 phenolic antiseptics (thymol, triclosan), 5 acidic analgesics or anti-inflammatories (ibuprofen
Ute I Scholl et al.
The Journal of clinical investigation, 127(7), 2739-2750 (2017-06-13)
Aldosterone-producing adenomas (APAs) are benign tumors of the adrenal gland that constitutively produce the salt-retaining steroid hormone aldosterone and cause millions of cases of severe hypertension worldwide. Either of 2 somatic mutations in the potassium channel KCNJ5 (G151R and L168R

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