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Merck
CN

21193

Calcium ionophore II

Selectophore, function tested

Synonym(s):

N,N,N′,N′-Tetra[cyclohexyl]diglycolic acid diamide, N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide, ETH 129

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About This Item

Empirical Formula (Hill Notation):
C28H48N2O3
CAS Number:
Molecular Weight:
460.69
UNSPSC Code:
26111700
NACRES:
NB.61
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6491651
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description

for ion-selective electrodes

Quality Level

product line

Selectophore

form

solid

quality

function tested

SMILES string

O=C(COCC(=O)N(C1CCCCC1)C2CCCCC2)N(C3CCCCC3)C4CCCCC4

InChI

1S/C28H48N2O3/c31-27(29(23-13-5-1-6-14-23)24-15-7-2-8-16-24)21-33-22-28(32)30(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h23-26H,1-22H2

InChI key

URAUKAJXWWFQSU-UHFFFAOYSA-N

General description

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Application

Selected application examples
Calcium ionophore II (ETH 129) was used in preparing calcium selective minielectrodes which are used in determination of dissociation constant (Kd).
Lipophilic ionophore for Ca2+-selective electrodes with detection limit in the sub-nanomolar range. Extremely efficient carrier of Ca2+-ions; induces a selectivity in membranes for Ca2+ over Mg2+ by a factor of about 104.
Suitable for intracellular calcium measurements.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Patrick C Bradshaw et al.
BMC biochemistry, 7, 4-4 (2006-02-08)
Divalent cations are required for many essential functions of mitochondrial metabolism. Yet the transporters that mediate the flux of these molecules into and out of the mitochondrion remain largely unknown. Previous studies in yeast have led to the molecular identification
Xiaoxue Liu et al.
Mikrochimica acta, 187(9), 525-525 (2020-08-29)
Ultrathin metallic WS2 (M-WS2) nanosheets and semiconductive WS2 (S-WS2) nanosheets were exfoliated and for the first time employed as ion-to-electron transducing layer to construct an all-solid-state ion-selective electrode. Importantly, we found that the transducing efficiency of WS2 nanosheet-based solid-contact layer is
Y L Ma et al.
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 12(2), 98-102 (1992-01-01)
A calcium ion-selective PVC membrane electrode based on neutral carrier n,n,n',n'-tetracyclohexyl-3-oxapetanediamide, using di-(2-ethylhexyl)phthalate as the plasticizer and potassium tetrakis (4-chlorophenyl) borate as the additive is reported in this paper. The ion selective membrane consists of 1 wt% of the Ca2+



Global Trade Item Number

SKUGTIN
21193-50MG-F04061838772060
21193-250MG-F04061832808468