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21620

Supelco

Disperse Blue 124

for microscopy

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CAS Number:
MDL number:
NACRES:
MA.02

grade

for microscopy

Quality Level

application(s)

environmental

format

neat

InChI

1S/C16H19N5O4S/c1-4-20(7-8-25-12(3)22)13-5-6-14(11(2)9-13)18-19-16-17-10-15(26-16)21(23)24/h5-6,9-10H,4,7-8H2,1-3H3

InChI key

HMAJVAFLGGPIPN-UHFFFAOYSA-N

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General description

Disperse Blue (DB) 124 is a strong clothing dye sensitizer. It is also an important textile dye allergen.

Application

DB 124 was used during testing the sensitizing potential of the dye using loose-fit coculture-based sensitization assay (LCSA).

Other Notes

Dye standard for the assay of allergy-releasing dyes in textiles

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ashley B Wentworth et al.
Dermatitis : contact, atopic, occupational, drug, 23(6), 269-274 (2012-11-22)
Recognition of allergic contact dermatitis attributed to textile dyes and resins is steadily increasing. This study aims to review the results of patch testing with a textile series at our institution and to compare with previously published reports. We performed
Kristina Ryberg et al.
Contact dermatitis, 60(5), 270-278 (2009-04-29)
Former investigations have demonstrated that patch test preparations containing Disperse Blue (DB) 106 and DB 124 are impure. To investigate the significance of impurities in preparations of disperse dyes with regard to contact allergy. 21 patients allergic to DB 106
Atypical presentation of textile dye sensitization.
C Pecquet et al.
Contact dermatitis, 40(1), 51-51 (1999-02-03)
Clothing dye dermatitis masquerading as (coexisting) mimosa allergy.
J D Guin et al.
Contact dermatitis, 40(1), 45-45 (1999-02-03)
Z Caliskaner et al.
Human & experimental toxicology, 31(1), 101-103 (2011-10-27)
Disperse blue (DB) 106 and DB 124 are the most frequent fabric dye allergens inducing textile dermatitis, but contact allergy to them may easily undiagnosed because the clinical picture usually needs high index of suspicion. We present the case of

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