Merck
CN
All Photos(1)

Documents

26454

Sigma-Aldrich

Magnesium stearate

puriss., meets analytical specification of Ph. Eur., BP, ≥90% stearic and palmitic acid basis, ≥40% stearic acid basis (GC), 4.0-5.0% Mg basis (calc on dry sub.)

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Stearic acid magnesium salt
Linear Formula:
[CH3(CH2)16CO2]2Mg
CAS Number:
557-04-0
Molecular Weight:
591.24
Beilstein:
3919702
EC Number:
209-150-3
MDL number:
MFCD00036391
PubChem Substance ID:
57648176
NACRES:
NA.22

grade

puriss.

Assay

≥40% stearic acid basis (GC)
≥90% stearic and palmitic acid basis
4.0-5.0% Mg basis (calc on dry sub.)

quality

meets analytical specification of Ph. Eur., BP

impurities

acidity or alkalinity, complies
 microbiological impurity, in accordance
 residual solvents, complies

loss

≤6.0% loss on drying, 105 °C

mp

200 °C (lit.)

acid value

195‑210(fatty acid)

solubility

alcohol: insoluble
diethyl ether: insoluble
water: insoluble

anion traces

chloride (Cl-): ≤1000 mg/kg
sulfate (SO42-): ≤5000 mg/kg

cation traces

Cd: ≤3 mg/kg
Ni: ≤5 mg/kg
Pb: ≤10 mg/kg

suitability

in accordance for fatty acid composition
passes test for identity

application(s)

pharmaceutical (small molecule)

SMILES string

CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2

InChI key

HQKMJHAJHXVSDF-UHFFFAOYSA-L

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Magnesium stearate has been used as a tablet and capsule lubricant. It has also been used for preparing microcapsules.

Biochem/physiol Actions

Magnesium stearate is the magnesium salt of stearic acid that possess lubricating properties and hence prevents ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets. Dry coating of drugs with magnesium stearate leads to flow improvement, flow-aid and lubrication effects, tabletability as well as non-inhibited dissolution rate.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

<BIG>Marleen de Veij</BIG>
Journal of Raman Spectroscopy, 40 (2008)
M J Amorim et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 52(1), 39-44 (2001-07-05)
Several different peptides and proteins, such as the pancreatic trypsin inhibitor, growth factors and trefoil peptides, are known to play important roles in maintaining the structure and function of the gastrointestinal wall. With the advent of recombinant biotechnology, it has
Ziyaur Rahman et al.
International journal of pharmaceutics, 475(1-2), 462-470 (2014-09-01)
Clinical performance of an amorphous solid dispersion (ASD) drug product is related to the amorphous drug content because of the greater bioavailability of this form of the drug than its crystalline form. Therefore, it is paramount to monitor the amorphous
Julia Grund et al.
International journal of pharmaceutics, 469(1), 94-101 (2014-04-22)
The objective of this study was to identify and evaluate key polymer properties affecting direct compression and drug release from water-insoluble matrices. Commonly used polymers, such as Kollidon(®) SR, Eudragit(®) RS and ethyl cellulose, were characterized, formulated into tablets and
A Kluk et al.
International journal of pharmaceutics, 485(1-2), 1-6 (2015-03-05)
Minitablets are a novel, multi-compartment solid drug formulation, particularly intended for children between 1 and 6 years of age. Available literature shows that even infants are capable of swallowing a single minitablet. In this study, we have explored the level
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service