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Merck
CN

281662

Diethylene glycol dimethyl ether

anhydrous, 99.5%

Synonym(s):

2-Methoxyethyl ether, Bis(2-methoxyethyl) ether, Dimethyldiglycol, Diglyme

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About This Item

Linear Formula:
(CH3OCH2CH2)2O
CAS Number:
Molecular Weight:
134.17
UNSPSC Code:
12352112
NACRES:
NA.21
PubChem Substance ID:
EC Number:
203-924-4
Beilstein/REAXYS Number:
1736101
MDL number:
Assay:
99.5%
Grade:
anhydrous
Bp:
162 °C (lit.)
Vapor pressure:
3 mmHg ( 20 °C)
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grade

anhydrous

Quality Segment

vapor density

4.6 (vs air)

vapor pressure

3 mmHg ( 20 °C)

assay

99.5%

form

liquid

autoignition temp.

370 °F

expl. lim.

17.4 %

impurities

<0.005% water

evapn. residue

<0.0005%

refractive index

n20/D 1.408 (lit.)

pH

7 (20 °C)

bp

162 °C (lit.)

mp

−64 °C (lit.)

density

0.944 g/mL at 20 °C (lit.), 0.939 g/mL at 25 °C (lit.)

SMILES string

COCCOCCOC

InChI

1S/C6H14O3/c1-7-3-5-9-6-4-8-2/h3-6H2,1-2H3

InChI key

SBZXBUIDTXKZTM-UHFFFAOYSA-N

General description

Our anhydrous solvents deliver exceptionally low water content, making them the ideal choice for moisture-sensitive laboratory applications. Packaged in the exclusive Sure/Seal™ septum bottle system, they are reliably protected against moisture ingress from first use to last drop. The innovative Sure/Seal™ closure combines an advanced plug-style liner with an airtight elastomer and crimp cap design to ensure consistent product integrity. Three unique liner materials provide optimal chemical compatibility across a broad range of solvents. Sure/Seal™ packaging is proven to maintain anhydrous conditions even after repeated punctures. With more than 70 products across all major solvent families, available in pack sizes from 100 mL to 2 L, the portfolio meets virtually every laboratory need. By choosing ready-to-use anhydrous solvents in Sure/Seal™ packaging, researchers eliminate the need for time-consuming and hazardous in-house solvent drying and distillation - saving time, reducing risk, and improving reproducibility.

Application

Anhydrous solvents in Sure/Seal™ packaging are essential wherever water contamination would compromise experimental results. They are widely used in moisture-sensitive applications such as organic synthesis - including Grignard reactions, organometallic chemistry, and catalysis - as well as in peptide, oligonucleotide, and pharmaceutical synthesis.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC


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Pictograms

FlameHealth hazard

Signal Word

Danger

Hazard Codes

Hazard Classifications

Flam. Liq. 3 - Repr. 1B

supp_hazards

Storage Class

3 - Flammable liquids

Flash Point (°F)

134.6 °F - closed cup

Flash Point (°C)

57 °C - closed cup

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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