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Merck
CN

293105

Tetrahydropyran

anhydrous, 99%

Synonym(s):

Pentamethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C5H10O
CAS Number:
Molecular Weight:
86.13
UNSPSC Code:
12352005
NACRES:
NA.21
PubChem Substance ID:
EC Number:
205-552-8
Beilstein/REAXYS Number:
102436
MDL number:
Assay:
99%
Grade:
anhydrous
Bp:
88 °C (lit.)
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grade

anhydrous

Quality Level

vapor density

3 (vs air)

assay

99%

form

liquid

impurities

<0.003% water, <0.005% water (100 mL pkg)

evapn. residue

<0.0003%

refractive index

n20/D 1.42 (lit.)

bp

88 °C (lit.)

mp

−45 °C (lit.)

density

0.881 g/mL at 25 °C (lit.)

SMILES string

C1CCOCC1

InChI

1S/C5H10O/c1-2-4-6-5-3-1/h1-5H2

InChI key

DHXVGJBLRPWPCS-UHFFFAOYSA-N

General description

Tetrahydropyran (THP) is a saturated cyclic ether. It is commonly used as a solvent in organic synthesis because of its strong hydrophobicity and low vaporization temperature, which enable easy recovery and reuse of the solvent. This makes the entire synthetic process more environmentally friendly.

Application

Tetrahydropyran can be used as a solvent in various classical organic reactions such as radical reactions, palladium-catalyzed coupling, and Grignard reactions.


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pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 2

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

3.2 °F - closed cup

flash_point_c

-16 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Flame chemistry of tetrahydropyran as a model heteroatomic biofuel.
Labbe NJ, et al.
Proceedings of the Combustion Institute, 34(3), 259-267 (2013)
Zhaotian Zhang et al.
International ophthalmology, 39(7), 1543-1551 (2018-06-24)
To introduce novel and easy techniques for 27-gauge silicone oil (SO) infusion and removal. Consecutive patients treated with 27-gauge pars plana vitrectomy (PPV) plus SO infusion (Infusion Group) and scheduled to have SO removal (Removal Group) were prospectively included, respectively.
Veysel Cankurtaran et al.
Bosnian journal of basic medical sciences, 17(1), 74-80 (2017-01-31)
Retinal detachment is the separation of the sensory retina from the retinal pigment epithelium by subretinal fluid. There are several types of retinal re-attachment surgery, including scleral buckling (SB), pneumatic retinopexy, and vitrectomy (with or without SB). The objective of



Global Trade Item Number

SKUGTIN
293105-6X1L04061837532610
293105-1L04061837532597
293105-100ML04061826595244
293105-2L04061837532603