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30122

L-Cysteine hydrochloride monohydrate

tested according to Ph. Eur.

Synonym(s):

Cysteini hydrochloridum monohydricum

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About This Item

Linear Formula:
HSCH2CH(NH2)COOH · HCl · H2O
CAS Number:
7048-04-6
Molecular Weight:
175.63
UNSPSC Code:
12352209
PubChem Substance ID:
329753438
eCl@ss:
32160406
EC Number:
200-157-7
Beilstein/REAXYS Number:
5158059
MDL number:
MFCD00065606
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Quality Level

100

agency

USP/NF, tested according to Ph. Eur.

assay

98.5-101.0%

form

solid

mp

176 °C

solubility

H2O: soluble 100 g/L at 25 °C

application(s)

pharmaceutical (small molecule)

SMILES string

O.Cl.N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1

InChI key

QIJRTFXNRTXDIP-JIZZDEOASA-N

Application

L-Cysteine hydrochloride monohydrate was used in the synthesis of polycarbophil-cysteine conjugate.

Biochem/physiol Actions

Cysteine is a non-essential, thiol-containing amino acid that has protective effects in normal tissues. It is converted to glutathione that decreases the effects of chemotherapeutic and radiation agents. This might restrict the effect of therapeutic agents used for cancer treatment.
NMDA glutamatergic receptor antagonist.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

M K Marschütz et al.
Pharmaceutical research, 17(12), 1468-1474 (2001-04-17)
To develop an oral controlled release system for insulin. The polymer-inhibitor conjugates carboxymethylcellulose (CMC)-Bowman-Birk inhibitor and CMC-elastatinal were homogenized with polycarbophil-cysteine conjugate, insulin, and mannitol, compressed to 2 mg microtablets and enteric coated with a polymethacrylate. The protective effect of
J C Roberts
Amino acids, 8(2), 113-124 (1995-06-01)
The thiol-containing amino acid, cysteine, and its analogs are useful for a variety of protective applications, including protecting normal tissues against the unwanted side effects of cancer chemotherapeutic agents and radiation treatment. The protection can result from both direct action
Matthew Oser et al.
Journal of cell science, 123(Pt 21), 3662-3673 (2010-10-26)
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells enriched in proteins that regulate actin polymerization. The on-off regulatory switch that initiates actin polymerization in invadopodia requires phosphorylation of tyrosine residues 421, 466, and 482 on cortactin. However, it is
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