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Merck
CN

31592

Amprolium hydrochloride

VETRANAL®, analytical standard

Synonym(s):

1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride

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About This Item

Linear Formula:
C14H19N4Cl · HCl
CAS Number:
137-88-2
Molecular Weight:
315.24
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753837
EC Number:
205-307-5
Beilstein/REAXYS Number:
4118699
MDL number:
MFCD00078831

Key Documents

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Product Name

Amprolium hydrochloride, VETRANAL®, analytical standard

InChI key

PJBQYZZKGNOKNJ-UHFFFAOYSA-M

InChI

1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

SMILES string

[Cl-].Cl[H].CCCc1ncc(C[n+]2ccccc2C)c(N)n1

grade

analytical standard

description

cationic

product line

VETRANAL®

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

mol wt

315.24 g/mol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ5864
BCCB9889
BCBV0662
BCBS9642V

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X Wang et al.
Neuroscience, 144(3), 1045-1056 (2006-12-02)
Thiamine (vitamin B1) deficiency (TD) causes region selective neuronal loss in the brain; it has been used to model neurodegeneration that accompanies mild impairment of oxidative metabolism. The mechanisms for TD-induced neurodegeneration remain incompletely elucidated. Inhibition of protein glycosylation, perturbation
Anna Martínez-Villalba et al.
Journal of chromatography. A, 1217(37), 5802-5807 (2010-08-11)
We present a fast liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the analysis of the coccidiostat amprolium in food samples. Tandem mass spectrometry in a triple quadrupole was used for quantitative purposes, and the information from multiple-stage mass spectrometry in
E Karagouni et al.
International journal of immunopathology and pharmacology, 18(1), 121-132 (2005-02-09)
The aim of the present study was to investigate the impact of a successful anti-myxosporean medication on the innate immune system of fish intensively cultured in the Mediterranean basin. For this purpose, juvenile and adult gilthead seabream (S. aurata L.)
Clara Lemos et al.
European journal of pharmacology, 682(1-3), 37-42 (2012-03-06)
The aim of this study was to characterize the intestinal absorption of thiamine, by investigating the hypothesis of an involvement of Organic Cation Transporter (OCT) family members in this process. [(3)H]-T(+) uptake was found to be: 1) time-dependent, 2) Na(+)-
D Bizon-Zygmańska et al.
Neurochemistry international, 59(2), 208-216 (2011-06-16)
Inhibition of pyruvate (PDHC) and ketoglutarate (KDHC) dehydrogenase complexes induced by thiamine pyrophosphate deficits is known cause of disturbances of cholinergic transmission in the brain, yielding clinical symptoms of cognitive, vegetative and motor deficits. However, particular alterations in distribution of
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