Skip to Content
Merck
CN

31622

Bithionol

VETRANAL®, analytical standard

Synonym(s):

2,2′-Thio-bis(4,6-dichlorophenol), Bis(2-hydroxy-3,5-dichlorophenyl) sulfide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C12H6Cl4O2S
CAS Number:
97-18-7
Molecular Weight:
356.05
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753850
EC Number:
202-565-0
Beilstein/REAXYS Number:
2003535
MDL number:
MFCD00055727

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Bithionol, VETRANAL®, analytical standard

InChI key

JFIOVJDNOJYLKP-UHFFFAOYSA-N

InChI

1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H

SMILES string

Oc1c(Cl)cc(Cl)cc1Sc2cc(Cl)cc(Cl)c2O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

antibiotic activity spectrum

parasites

application(s)

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

mode of action

enzyme | inhibits
protein synthesis | interferes

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Bithionol has been used as reference standard for measuring the concentration of antihelmintic substance in pharmacy products using HPLC.2
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Bithionol is a dichlorophenol compound that shows antimicrobial property.1
Chemical structure: diphenylsulfide

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCG4854
BCBW2025

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ok-Jae Lee et al.
Journal of gastroenterology and hepatology, 21(10), 1631-1633 (2006-08-25)
Fascioliasis is not common in humans and, furthermore, its ectopic migration into the pancreas is extremely rare. A definitive diagnosis of ectopic fascioliasis is based on the demonstration of flukes in the affected organ. If the flukes invade the parenchyma
Bo Yang et al.
Neuropharmacology, 51(4), 896-906 (2006-08-01)
The Slack (Sequence like a calcium-activated K channel) (Slo2.2) gene is abundantly expressed in the mammalian brain and encodes a sodium-activated K+ (KNa) channel. Although the specific roles of Slack channel subunits in neurons remain to be identified, they may
E Durbize et al.
Contact dermatitis, 48(3), 144-149 (2003-05-21)
Contact photoallergy to ketoprofen gels has been widely reported, and cross-sensitivity reactions with other compounds, such as tiaprofenic acid, fenofibrate and benzophenones, are well known. However, positive photopatch tests to other different non-benzophenone-related compounds have recently been observed. We report
C Perez et al.
Journal of the American Academy of Dermatology, 42(5 Pt 2), 900-902 (2000-04-18)
Eosinophilic panniculitis is characterized by a prominent infiltration of subcutaneous fat with eosinophils. We report a case of Fasciola hepatica infection presenting with eosinophilic panniculitis successfully treated with bithionol. To our knowledge, this is the first report of recurrent eosinophilic
L Reid et al.
Toxicology in vitro : an international journal published in association with BIBRA, 15(4-5), 441-445 (2001-09-22)
Exposure to hydrogen peroxide causes oxidative stress in keratinocytes. Previous work has shown that the antiparasitic drug bithionol has an EC(50) of 0.7 microg/ml (2 microM) with primary human keratinocytes, but that these cells do not respond to photoactivated bithionol.
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service