32173
Ipronidazole
VETRANAL®, analytical standard
Synonym(s):
1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole, 2-Isopropyl-1-methyl-5-nitroimidazol, NSC 109212, Ro 07-1554
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About This Item
Empirical Formula (Hill Notation):
C7H11N3O2
CAS Number:
Molecular Weight:
169.18
Beilstein:
744577
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
analytical standard
Quality Level
product line
VETRANAL®
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
format
neat
SMILES string
[N+](=O)([O-])c1[n](c(nc1)C(C)C)C
InChI
1S/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H3
InChI key
NTAFJUSDNOSFFY-UHFFFAOYSA-N
General description
Ipronidazole is a veterinary drug, which is widely used in controlling histomoniasis in turkeys.
Application
Ipronidazole may be used as a reference standard in the determination of ipronidazole in tissue samples using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC) and thermospray tandem mass spectrometry (HPLC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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J E Roybal et al.
Journal - Association of Official Analytical Chemists, 70(4), 626-630 (1987-07-01)
A simple and rapid method is described for the determination of dimetridazole (DMZ) and ipronidazole (IPR) in swine feeds at various levels (0.11-110 ppm). The drugs are released from feed by prewetting with a buffer, followed by extraction with either
B Abbitt et al.
Journal of the American Veterinary Medical Association, 188(1), 67-69 (1986-01-01)
Two of 3 adult Greyhounds with clinical signs of giardiasis were treated by the addition of ipronidazole hydrochloride to their water supply (126 mg/L) for 7 days. Within 15 hours, the dogs had improved clinically, and large numbers of degenerating
W J Morris et al.
Journal - Association of Official Analytical Chemists, 70(4), 630-634 (1987-07-01)
Extracts from 4 types of swine feed containing 0.11 ppm each of dimetridazole (DMZ) and ipronidazole (IPR) were analyzed by capillary gas chromatography/mass spectrometry (GC/MS) using multiple ion detection (MID) techniques. We demonstrate in this paper that the quantitative results
Identification of dimetridazole, ipronidazole, and their alcohol metabolites in turkey tissues by thermospray tandem mass spectrometry.
Matusik EJ, et al.
Journal of Agricultural and Food Chemistry, 40(3), 439-443 (1992)
Determination of ipronidazole and its principal metabolite in turkey skin and muscle by combined gas chromatography-negative chemical ionization mass spectrometry-stable isotope dilution.
W A Garland et al.
Journal of agricultural and food chemistry, 28(2), 273-277 (1980-03-01)
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