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Merck
CN

32379

Zilpaterol hydrochloride

VETRANAL®, analytical standard

Synonym(s):

(6RS,7RS)-4,5,6, 7-Tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[ 4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O2 · HCl
CAS Number:
119520-06-8
Molecular Weight:
297.78
MDL number:
MFCD18782610
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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Product Name

Zilpaterol hydrochloride, VETRANAL®, analytical standard

SMILES string

Cl.[n]21c3c(nc2O)cccc3[C@H]([C@@H](CC1)NC(C)C)O

InChI

1S/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19;/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19);1H/t11-,13-;/m1./s1

InChI key

GIEFXLLRTJNFGT-LOCPCMAASA-N

grade

analytical standard

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

Zilpaterol hydrochloride analytical standard can be used as follows:
  • Determination of zilpaterol in cattle plasma and tissue samples using solid phase extraction (SPE) well plate of 96 samples for sample preparation and subsequent analysis by liquid chromatography-triple quadrupole mass spectrometry (LC-MS/MS)
  • Multi-residue analysis of 3 β-agonists, zilpaterol, clenbuterol, and ractopamine in a variety of meat samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • QuEChERS-based preparation of two types of animal tissue samples, muscle and viscera, for the analysis of seven β-agonists by liquid chromatography/tandem mass spectrometry
  • Development and validation of an LC-MS/MS method to estimate zilpaterol, ractopamine, and clenbuterol in bovine tissue samples
  • Simultaneous quantitative determination of spectinomycin, halquinol, zilpaterol, and melamine in animal feed samples by LC-MS/MS

General description

Zilpaterol belongs to the group of β-adrenergic agonists, used in the treatment of lung diseases due to its brochodilating nature. It is also widely used in veterinary medicine as a growth promoter for increasing muscle gain and decreasing fat.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

兴奋剂蛋白同化制剂
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Certificates of Analysis (COA)

Lot/Batch Number
BCCK4314
BCCG5268
BCCB0050
BCBW7338
BCBT9832

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Evaluation of Certain Veterinary Drug Residues in Food: Eighty-first Report of the Joint FAO/WHO Expert Committee on Food Additives (2016)
Natalia Cernicchiaro et al.
Foodborne pathogens and disease, 13(9), 517-525 (2016-06-16)
The efficacy of a Salmonella vaccine for reducing fecal shedding of Salmonella during the finishing period and lymph node (LN) carriage at harvest was investigated in commercial feedlot cattle. The study was designed as a pen-level randomized complete block with
P J Kononoff et al.
Journal of animal science, 95(1), 194-200 (2017-02-09)
A total of 2,948 steers (mean initial BW = 568.9 ± 49.4 kg) were used to evaluate the effect of the LEP R25C SNP genotype on feed intake, growth performance, and carcass characteristics over time. Steers were grouped into 5
J A Hagenmaier et al.
Journal of animal science, 94(12), 5064-5076 (2017-01-04)
Feedlot cattle ( = 1,395; BW = 568 ± 43 kg) were used to evaluate the effects of shade on animal welfare, growth performance, and carcass quality during the summer of 2013 in a Kansas commercial feedlot. Seven lots of
Ennet Moholisa et al.
Journal of the science of food and agriculture, 97(8), 2375-2381 (2016-10-08)
Animal age as determined by number of permanent incisors (p. i.) is used in classification of beef carcasses to describe expected meat tenderness. However, animals differing in age are reared under different production systems (pasture or feedlot). In addition to
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