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Merck
CN

32422

Ceftiofur hydrochloride

VETRANAL®, analytical standard

Synonym(s):

(6R,7R)-7-{[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino}-3-{[(2-furanylcarbonyl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride, 3-[(2-Furylcarbonyl)thio]methyl]-7-[2-(2-amino-4-thiazolyl)-2-(methoxyiminoacetamido)-3-cephem-4-carboxylic acid hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C19H17N5O7S3 · HCl
CAS Number:
103980-44-5
Molecular Weight:
560.02
NACRES:
NA.24
PubChem Substance ID:
329754200
UNSPSC Code:
41116107
MDL number:
MFCD04038020

Key Documents

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InChI

1S/C19H17N5O7S3.ClH/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10;/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28);1H/b23-11-;/t12-,16-;/m1./s1

SMILES string

Cl.CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSC(=O)c3ccco3)=C(N2C1=O)C(O)=O)c4csc(N)n4

InChI key

KEQFDTJEEQKVLM-JUODUXDSSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCL2502
BCCH1294
BCCB8697
BCBZ8753
BCBS3479V

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M L Macpherson et al.
Journal of veterinary pharmacology and therapeutics, 36(1), 59-67 (2012-03-28)
The objective of this study was to determine the pharmacokinetics of CCFA in mares with placentitis and evaluate the disposition of the drug in fetal fluids, fetal membranes, colostrum, and serum of foals. A secondary objective was to obtain pilot
Katharine L Hope et al.
American journal of veterinary research, 73(5), 620-627 (2012-04-27)
To determine the pharmacokinetic properties of 1 IM injection of ceftiofur crystalline-free acid (CCFA) in American black ducks (Anas rubripes). 20 adult American black ducks (6 in a preliminary experiment and 14 in a primary experiment). Dose and route of
J E Dechant et al.
Journal of veterinary pharmacology and therapeutics, 36(2), 122-129 (2012-04-11)
Six adult male alpacas received one subcutaneous administration of ceftiofur crystalline free acid (CCFA) at a dosage of 6.6 mg/kg. After a washout period, the same alpacas received three subcutaneous doses of 6.6 mg/kg CCFA at 5-day intervals. Blood samples
L Oliveira et al.
Journal of dairy science, 95(4), 1913-1920 (2012-03-31)
Antimicrobials are often used for treatment of bovine mastitis and the possibility of selection for resistant bacteria must be considered. The objectives of this study were to determine the minimum inhibitory concentration of Staphylococcus aureus recovered from cases of clinical
M Probo et al.
Journal of dairy science, 101(10), 9419-9429 (2018-08-21)
The objective of this study was to assess the association between individual metabolic diseases (MD) and multiple MD (MD+) in the transition period (±3 wk relative to calving) and the culling risk in the first 120 d in milk (DIM)
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