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Merck
CN

32434

TEPP

PESTANAL®, analytical standard

Synonym(s):

Tetraethyl pyrophosphate, Tetraethyl diphosphate

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About This Item

Empirical Formula (Hill Notation):
C8H20O7P2
CAS Number:
107-49-3
Molecular Weight:
290.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329754210
EC Number:
203-495-3
Beilstein/REAXYS Number:
1714017
MDL number:
MFCD00055459

Key Documents

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InChI

1S/C8H20O7P2/c1-5-11-16(9,12-6-2)15-17(10,13-7-3)14-8-4/h5-8H2,1-4H3

SMILES string

CCOP(=O)(OCC)OP(=O)(OCC)OCC

InChI key

IDCBOTIENDVCBQ-UHFFFAOYSA-N

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

Quality Level

100

Related Categories

General description

TEPP (Tetraethyl pyrophosphate, Pestanal) is highly toxic in nature both by skin absorption and inhalation. It is an organic phosphate pesticide, acting acts as an inhibitor of cholinesterase. It is soluble in water and is slowly decomposed by water. It may be found as a dry mixture or in the liquid state.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

>212.0 °F

flash_point_c

> 100 °C

Regulatory Information

农药列管产品
剧毒化学品
危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7783
BCCL6667
BCCJ8324
BCBW7851
BCBW3672

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Reversal of the actions of tetraethyl pyrophosphate in surviving mammalian tissue.
B B ROY et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 89(2), 255-258 (1955-06-01)
[Etiology of peptic ulcer under the influence of cholinesterase poisons].
R JAQUES
Helvetica physiologica et pharmacologica acta, 12(2), C 24-C 26 (1954-01-01)
Tetraethyl pyrophosphate in the myasthenia gravis.
O J NOVOTA
Missouri medicine, 49(2), 133-134 (1952-02-01)
Studies on the mechanism of action of DFP and TEPP.
B P McNAMARA et al.
The Journal of pharmacology and experimental therapeutics, 110(2), 232-240 (1954-02-01)
J U Patel et al.
Journal of pharmaceutical sciences, 83(10), 1477-1481 (1994-10-01)
An O-(saccharinylmethyl) prodrug was synthesized to improve the poor oral potency of the phenolic drug 17 beta-estradiol. This O-(imidomethyl) type of prodrug was designed to undergo chemical hydrolysis and to be a poor substrate for enzymatic hydrolysis. At 37 degrees
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