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Merck
CN

32553

Tinidazole

VETRANAL®, analytical standard

Synonym(s):

1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C8H13N3O4S
CAS Number:
Molecular Weight:
247.27
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
243-014-4
Beilstein/REAXYS Number:
618182
MDL number:
Technical Service
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Quality Level

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O

InChI

1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3

InChI key

HJLSLZFTEKNLFI-UHFFFAOYSA-N

General description

Tinidazole belongs to the family of nitroimidazole compounds.

Application

Tinidazole may be used as an analytical reference standard for the determination of the analyte in:
  • Tablet formulations and human serum samples by reversed phase-high performance liquid chromatography (RP-HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2 - Muta. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Separation and assay o f antiprotozoal imidazole derivatives (metronidazole, tinidazole and secnidazole) by RP-HPLC.
Alhalabi Z, et al.
International Journal of Pharmaceutical Sciences Review and Research, 13(1), 13-18 (2012)
Alessandro Federico et al.
Gastroenterology, 143(1), 55-61 (2012-04-10)
Helicobacter pylori have become resistant to antimicrobial agents, reducing eradication rates. A 10-day sequential regimen that contains levofloxacin was efficient, safe, and cost saving in eradicating H pylori infection in an area with high prevalence of clarithromycin resistance. We performed
Elizabeth A Bosserman et al.
Sexually transmitted diseases, 38(10), 983-987 (2011-09-22)
Antimicrobial resistance is one of the causes of treatment failure in women after standard nitroimidazole therapy for Trichomonas vaginalis infections. The Centers for Disease Control and Prevention provides drug susceptibility testing and guidance for treatment failures but the efficacy of



Global Trade Item Number

SKUGTIN
32553-10MG04061826713105