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Merck
CN

32555

Xylazine-d6

VETRANAL®, analytical standard

Synonym(s):

2-(2,6-Dimethyl-d6-phenylamino)-5,6-dihydro-4H-thiazine

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About This Item

Empirical Formula (Hill Notation):
C12D6H10N2S
CAS Number:
Molecular Weight:
226.37
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI

1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)/i1D3,2D3

SMILES string

[2H]C([2H])([2H])c1cccc(c1NC2=NCCCS2)C([2H])([2H])[2H]

InChI key

BPICBUSOMSTKRF-WFGJKAKNSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

mass shift

M+6

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Xylazine-d6 may be used as an analytical standard for the determination of xylazine in:
  • Rat brain samples by liquid-liquid extraction (LLE) and gas chromatography-mass spectrometry (GC-MS).
  • Water samples by isotope-dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Comparative behavioral toxicology with two common larval fish models: Exploring relationships among modes of action and locomotor responses.
Steele WB, et al.
The Science of the Total Environment, 640, 1587-1600 (2018)
Elodie Bonfanti et al.
Journal of pharmacological and toxicological methods, 77, 6-9 (2015-09-13)
In human and veterinary medicine, the injectable drugs ketamine and xylazine are mainly used in combination to induce, and then maintain general anaesthesia; they also provide pain and stress relief. Some side-effects have been reported on the auditory brainstem response
Measurement of ketamine and xylazine in rat brain by liquid-liquid extraction and gas chromatography-mass spectrometry.
Bonfanti E, et al.
Journal of Pharmacological and Toxicological Methods, 77, 6-9 (2016)

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