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Merck
CN

32593

Cambendazole

VETRANAL®, analytical standard

Synonym(s):

Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C14H14N4O2S
CAS Number:
26097-80-3
Molecular Weight:
302.35
Beilstein:
563292
EC Number:
247-459-5
MDL number:
MFCD00864552
UNSPSC Code:
41116107
PubChem Substance ID:
329754047
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)OC(=O)Nc1ccc2[nH]c(nc2c1)-c3cscn3

InChI

1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)

InChI key

QZWHWHNCPFEXLL-UHFFFAOYSA-N

Related Categories

General description

Cambendazole is classified under the family of benzimidazole anthelmintic compounds.

Application

Cambendazole may be used as an analytical reference standard for the determination of the analyte in:
  • Bovine muscle samples by ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS/MS) operating in ESI mode.
  • Bovine milk samples by LC-ESI-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361fd

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8647
BCCK1453
BCCF0930
BCBZ9917
BCBW6201

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G C Coles et al.
Research in veterinary science, 45(1), 50-53 (1988-07-01)
The growth, using freshly cultured Escherichia coli with ampicillin or heat-treated lyophilised E coli as a food source, of the larvae of the mouse nematode Nematospiroides dubius and the infectivity of resulting third stage larvae were determined. Concentrations of E
R F Bento et al.
Revista do Instituto de Medicina Tropical de Sao Paulo, 35(4), 373-375 (1993-07-01)
A 15 year old male patient was diagnosed as being infected with the nematode Lagochilascaris minor, presenting as abscesses over the left mastoid region, and invading the temporal bone, mastoid sinuses and possibly the CNS. Surgical drainage and administration of
Ruggedness testing and validation of a practical analytical method for> 100 veterinary drug residues in bovine muscle by ultrahigh performance liquid chromatography-tandem mass spectrometry.
Geis-Asteggiante L, et al.
Journal of Chromatography A, 1258(1-2), 43-54 (2012)
Strongyloides ratti and S. stercoralis: effects of cambendazole, thiabendazole and mebendazole in vitro.
D I Grove et al.
Revista do Instituto de Medicina Tropical de Sao Paulo, 28(2), 97-103 (1986-03-01)
D I Grove et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 82(1), 146-149 (1988-01-01)
The effects of three benzimidazole anthelmintics in dogs infected with a human strain of Strongyloides stercoralis were investigated. Cambendazole, but not thiabendazole or mebendazole, abrogated the subsequent development of a patent infection when administered at the same time as infection
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