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Merck
CN

32802

Triclabendazole

VETRANAL®, analytical standard

Synonym(s):

5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole

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About This Item

Empirical Formula (Hill Notation):
C14H9Cl3N2OS
CAS Number:
68786-66-3
Molecular Weight:
359.66
NACRES:
NA.24
PubChem Substance ID:
329754333
UNSPSC Code:
41116107
MDL number:
MFCD00864519

Key Documents

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InChI key

NQPDXQQQCQDHHW-UHFFFAOYSA-N

SMILES string

CSc1nc2cc(Cl)c(Oc3cccc(Cl)c3Cl)cc2[nH]1

InChI

1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

100

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General description

Chemical structure: benzimidazole

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH3573
BCCC1583
BCBS2918V

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Michaela Haider et al.
Veterinary parasitology, 187(3-4), 445-451 (2012-03-03)
During the past decade, Fascioloides magna, the large American liver fluke, has spread within free-living deer in wetlands of the Danube in Lower Austria. The aim of this study was to determine the current infection rates with F. magna and
Access to medicines for orphan diseases: experience in the management of a case of Fasciola hepatica in Mumbai, Maharashtra, India.
U M Thatte et al.
The National medical journal of India, 25(4), 234-235 (2013-01-03)
Ali Farahnak et al.
Acta medica Iranica, 50(3), 164-168 (2012-03-16)
Fascioliasis is an endemic disease in Iran and triclabendazole (TCBZ) is using for treatment of domestic animals and infected people. Excretory-secretory products (ESP) play an important role in the host biochemical defense by means of activities of detoxifying and antioxidant
Miguel M Cabada et al.
Current opinion in infectious diseases, 25(5), 518-522 (2012-06-30)
This review focuses on the recent developments in the epidemiology, burden of disease, diagnostic tests, and treatment of fascioliasis. Recent epidemiologic data suggest that either the endemic areas are expanding or disease is being recognized in areas where it was
Richard Wilkinson et al.
Molecular and biochemical parasitology, 186(1), 69-72 (2012-09-18)
Control of fasciolosis is threatened by the development of anthelmintic resistance. Enhanced triclabendazole (TCBZ) efflux by ABC transporters such as P-glycoprotein (Pgp) has been implicated in this process. A putative full length cDNA coding for a Pgp expressed in adult
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