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Merck
CN

32904

Cefalonium hydrate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H18N4O5S2 · xH2O
CAS Number:
Molecular Weight:
458.51 (anhydrous basis)
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
226-948-7
MDL number:
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InChI

1S/C20H18N4O5S2.H2O/c21-17(26)11-3-5-23(6-4-11)9-12-10-31-19-15(18(27)24(19)16(12)20(28)29)22-14(25)8-13-2-1-7-30-13;/h1-7,15,19H,8-10H2,(H3-,21,22,25,26,28,29);1H2/t15-,19-;/m1./s1

InChI key

GVIOXNHDFXYYMP-AEFICSSHSA-N

SMILES string

O.NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)Cc4cccs4)C3=O)C([O-])=O)cc1

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

General description

Cefalonium is a cephalosporin antibiotic which belongs to the β-lactam class, used in both human and veterinary medicine. Its mode of action involves inhibiting of enzymes involved in the biosynthesis of cell wall peptidoglycan resulting in the lysis of bacteria.
Chemical structure: β-lactam

Application

Cefalonium hydrate may be used for the determination of cefalonium in bovine muscle by liquid chromatography coupled to tandem mass spectrometry.
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品
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[Effect of and length of protection offered by Cepravin Dry Cow in the prevention of summer-mastitis (author's transl)].
J Sol et al.
Tijdschrift voor diergeneeskunde, 107(12), 466-474 (1982-06-15)
A J Bradley et al.
Journal of dairy science, 93(4), 1566-1577 (2010-03-27)
The dry period is a critical time in the lactation cycle, being the optimum time to cure existing intramammary infection (IMI) as well as encompassing the periods of highest susceptibility to new infection. Currently, IMI in the dry period is
A comparative field trial of cephalonium and cloxacillin for dry cow therapy for mastitis in Australian dairy cows.
M D Wraight
Australian veterinary journal, 83(1-2), 103-103 (2005-06-24)
R W Shephard et al.
Australian veterinary journal, 82(10), 624-629 (2005-05-13)
To investigate and compare the therapeutic efficacy of dry cow agents containing either cephalonium or cloxacillin within Australian dairy herds. A treatment-control trial. Milk from infected quarters of cows with high somatic cell counts in milk on eight Australian dairy
Change in treatment to calving interval for Cepravin Dry Cow.
Andrew Montgomery
The Veterinary record, 155(1), 32-32 (2004-07-22)

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