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Merck
CN

32991

Lanoconazole

VETRANAL®, analytical standard

Synonym(s):

2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile

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About This Item

Empirical Formula (Hill Notation):
C14H10ClN3S2
CAS Number:
101530-10-3
Molecular Weight:
319.83
NACRES:
NA.24
PubChem Substance ID:
329754426
UNSPSC Code:
41116107
MDL number:
MFCD00865590

Key Documents

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InChI key

ZRTQSJFIDWNVJW-WYMLVPIESA-N

SMILES string

Clc1ccccc1C2CS\C(S2)=C(\C#N)n3ccnc3

InChI

1S/C14H10ClN3S2/c15-11-4-2-1-3-10(11)13-8-19-14(20-13)12(7-16)18-6-5-17-9-18/h1-6,9,13H,8H2/b14-12+

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

100

Related Categories

General description

Lanoconazole is a member of the imidazole family and an antifungal agent, which finds applications as an antidermatophytic drug.

Application

Lanoconazole may be used as a reference standard in the determination of lanoconazole in pharmaceutical formulations using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UV).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG1057
BCCC4640
BCBV5216

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Toshihiro Akihisa et al.
Journal of oleo science, 59(7), 351-360 (2010-06-02)
The content and composition of triterpene alcohol fractions of the non-saponifiable lipids (NSL) along with the fatty acid composition of the kernel fats (n-hexane extracts) of the shea tree (Vitellaria paradoxa; Sapotaceae) were determined for 36 samples from seven sub-Saharan
Allergic contact dermatitis due to lanoconazole with no cross-reactivity to other imidazoles.
S Taniguchi et al.
Dermatology (Basel, Switzerland), 196(3), 366-366 (1998-06-11)
Daisuke Todokoro et al.
Cornea, 38(2), 238-242 (2018-11-14)
Fungal keratitis can be difficult to medically treat. Topical antifungals are usually applied empirically as the initial option in treating fungal keratitis. Natamycin (NAT) and/or voriconazole (VRCZ) have been widely used in the treatment of fungal keratitis. However, Fusarium solani
Yoshiyuki Tatsumi et al.
Microbiology and immunology, 46(7), 433-439 (2002-09-12)
We developed a new technique for culture study that successfully recovers fungi from drug-treated skin tissues, in which tissue specimens were homogenized, dialyzed against water, digested with trypsin, and then washed with PBS, to eliminate the drug that remaining in
Fisher's Contact Dermatitis (2008)
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