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Merck
CN

33497

Sarafloxacin hydrochloride hydrate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H17F2N3O3 · HCl · xH2O
CAS Number:
91296-87-6
Molecular Weight:
421.83 (anhydrous basis)
MDL number:
MFCD03427297
UNSPSC Code:
41116107
PubChem Substance ID:
24860273
NACRES:
NA.24

Key Documents

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Product Name

Sarafloxacin hydrochloride hydrate, VETRANAL®, analytical standard

SMILES string

Fc1ccc(cc1)N2c3c(cc(c(c3)N4CCNCC4)F)C(=O)C(=C2)C(=O)O.[Cl-].[H+]

InChI

1S/C20H17F2N3O3.ClH/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24;/h1-4,9-11,23H,5-8H2,(H,27,28);1H

InChI key

KNWODGJQLCISLC-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8728
BCCF1230
BCBW7230
BCBW2994

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Eric Verdon et al.
Journal of AOAC International, 88(4), 1179-1192 (2005-09-15)
Quinolone antibacterials are veterinary drugs authorized for use in food animal production. The analysis of residual amounts of drugs in food from animal origin is important for quality control of products for consumers. For this purpose, Maximum Residue Limits (MRLs)
Priscilla Henno et al.
American journal of physiology. Lung cellular and molecular physiology, 300(6), L831-L839 (2011-03-08)
Pulmonary vascular remodeling and dysfunction associated to tobacco smoking might pave the way for the subsequent development of pulmonary hypertension. Its prognosis is dreadful and its underlying mechanisms are so far largely unknown in humans. To assess the potential role
Jeong-Heui Choi et al.
Biomedical chromatography : BMC, 25(3), 405-411 (2010-07-06)
In this study, a method for the detection of sarafloxacin in pig and chicken muscles was developed using HPLC-FLD as a regulatory residue technique. Good extraction efficiency was achieved using a mixture of 1% orthophosphoric acid-0.2 m MgCl(2) in water
Patrik Rossi et al.
Intensive care medicine, 34(5), 873-880 (2008-01-25)
To analyze the effect of endothelin-1 on pulmonary arterial and venous contractile force in vitro and on up- and downstream pulmonary vascular resistance in vivo under sham and endotoxemic conditions in pigs. In vitro: paired preparations of pulmonary arteries and
Linlin Dong et al.
Se pu = Chinese journal of chromatography, 23(3), 285-288 (2005-08-30)
A reversed-phase high performance liquid chromatographic method with fluorescence detection was developed for the simultaneous analysis of ciprofloxacin, danofloxacin, enrofloxacin and sarafloxacin residues in edible chicken tissues. The analytes were extracted from chicken muscle, skin and fat, liver, kidney by
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