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33656

Semicarbazide hydrochloride

VETRANAL®, analytical standard

Synonym(s):

N-Aminourea hydrochloride, Hydrazine carboxamide hydrochloride

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About This Item

Linear Formula:
NH2CONHNH2 · HCl
CAS Number:
563-41-7
Molecular Weight:
111.53
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329754605
EC Number:
209-247-0
Beilstein/REAXYS Number:
3593642
MDL number:
MFCD00013009
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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

175-177 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl.NNC(N)=O

InChI

1S/CH5N3O.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H

InChI key

XHQYBDSXTDXSHY-UHFFFAOYSA-N

Application

Semicarbazide hydrochloride may be used in the synthesis of 4-nitrobenzaldehyde semicarbazone via reaction with 4-nitrobenzaldehyde.
Semicarbazide hydrochloride may be used as a stabilizing agent for the determination of norepinephrine in plasma samples using stable-isotope dilution gas chromatography-tandem mass spectrometry with negative ion chemical ionization.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Oral

target_organs

Bone

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP2633
BCCP2634
BCCG5699
BCCG5696
BCBV0190

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Determination of norepinephrine in small volume plasma samples by stable-isotope dilution gas chromatography-tandem mass spectrometry with negative ion chemical ionization.
Kuhlenbeck LD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 738(2), 319-330 (2000)
Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography?tandem mass spectrometry
Leitner A, et al.
Journal of Chromatography A, 939, 49-58 (2001)
Jainendra Jain et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 6(1), 44-50 (2010-04-21)
A series of novel (+/-) 3-menthone semi carbazides (1-7) and thiosemicarbazides synthesized using an appropriate synthetic route and characterized by thin layer chromatography and spectral analysis. The anticonvulsant activity of synthesized compounds was established after intraperitoneal administration in three seizure
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Global Trade Item Number

SKUGTIN
33656-100MG-R04061826743058