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Carprofen

VETRANAL®, analytical standard

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Synonym(s):
6-Chloro-α-methyl-9H-carbazole-2-acetic acid
Empirical Formula (Hill Notation):
C15H12ClNO2
CAS Number:
53716-49-7
Molecular Weight:
273.71
EC Number:
258-712-4
MDL number:
MFCD00079028
PubChem Substance ID:
329754715
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

InChI key

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

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General description

Carprofen, is a non-steroidal anti-inflammatory drug, generally used to treat degenerative joint disease like canine osteoarthritis in animals. It can also be used like an analgesic agent to control the postoperative pain produced, during ovariohysterectomy in cats.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Angelo D Favia et al.
Journal of medicinal chemistry, 55(20), 8807-8826 (2012-10-10)
Pain and inflammation are major therapeutic areas for drug discovery. Current drugs for these pathologies have limited efficacy, however, and often cause a number of unwanted side effects. In the present study, we identify the nonsteroidal anti-inflammatory drug carprofen as
Paulin Jirkof et al.
Laboratory animals, 46(4), 325-334 (2012-10-26)
Individual housing of laboratory mice may increase vulnerability to surgical stress, and interfere with postsurgical recovery. To analyse the effect of housing conditions on recovery, pair- and single-housed female C57BL/6J mice underwent a minor laparotomy +/- analgesia, anaesthesia only or
D C Brown et al.
Journal of veterinary internal medicine, 27(1), 22-30 (2013-01-15)
Lameness assessment using force plate gait analysis (FPGA) and owner assessment of chronic pain using the Canine Brief Pain Inventory (CBPI) are valid and reliable methods of evaluating canine osteoarthritis. There are no studies comparing these 2 outcome measures. Evaluate
Lynn C Matsumiya et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 51(1), 42-49 (2012-02-15)
Postoperative pain management in animals is complicated greatly by the inability to recognize pain. As a result, the choice of analgesics and their doses has been based on extrapolation from greatly differing pain models or the use of measures with
Sarah Malek et al.
BMC veterinary research, 8, 185-185 (2012-10-06)
Pain and impaired mobility because of osteoarthritis (OA) is common in dogs and humans. Efficacy studies of analgesic drug treatment of dogs with naturally occurring OA may be challenging, as a caregiver placebo effect is typically evident. However, little is
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