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Merck
CN

33979

Robenidine hydrochloride

VETRANAL®, analytical standard

Synonym(s):

1,3-Bis[(4-chlorobenzylidene)amino]guanidine monohydrochloride

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About This Item

Empirical Formula (Hill Notation):
C15H13Cl2N5 · HCl
CAS Number:
Molecular Weight:
370.66
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
247-307-8
MDL number:
Technical Service
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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].Clc1ccc(cc1)\C=N\NC(=N)N\N=C\c2ccc(Cl)cc2

InChI

1S/C15H13Cl2N5.ClH/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12;/h1-10H,(H3,18,21,22);1H/b19-9+,20-10+;

InChI key

LTWIBTYLSRDGHP-HCURTGQUSA-N

General description

Robenidine hydrochloride is a coccidiostat and antibiotic, used in controlling coccidiosis.

Application

Robenidine hydrochloride has been used as a reference standard in the determination of robenidine hydrochloride in eggs using online solid-phase extraction with liquid chromatography coupled with tandem mass spectrometry (SPE-LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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R Brun et al.
Tropical medicine & international health : TM & IH, 6(5), 362-368 (2001-05-12)
CGP 40 215 is an inhibitor of S-adenosylmethionine decarboxylase, a key enzyme in trypanosomal polyamine biosynthesis. It is highly active against Trypanosoma brucei rhodesiense and T. b. gambiense in vitro and in the corresponding rodent models, and therefore was a
Martin Hansen et al.
Environmental pollution (Barking, Essex : 1987), 157(2), 474-480 (2008-11-04)
The antibacterial potency of eight anticoccidial drugs was tested in a soil bacteria bioassay (pour plate method), EC(50)-values between 2.4 and 19.6 microM were obtained; however, one compound, nicarbazin exhibited an EC(50)-value above the maximum tested concentration (21 microM, 9.1
Robin Das Gupta et al.
Antimicrobial agents and chemotherapy, 49(7), 2857-2864 (2005-06-28)
The intraerythrocytic development of Plasmodium falciparum correlates with increasing levels of the polyamines putrescine, spermidine, and spermine in the infected red blood cells; and compartmental analyses revealed that the majority is associated with the parasite. Since depletion of cellular polyamines



Global Trade Item Number

SKUGTIN
33979-100MG-R04061835560387