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Merck
CN

33981

Febantel

VETRANAL®, analytical standard

Synonym(s):

N-{2-[2,3-Bis-(methoxycarbonyl)-guanido]-5-(phenylthio)-phenyl}-2-methoxyacetamide

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About This Item

Empirical Formula (Hill Notation):
C20H22N4O6S
CAS Number:
58306-30-2
Molecular Weight:
446.48
NACRES:
NA.24
PubChem Substance ID:
329754720
UNSPSC Code:
41116107
EC Number:
261-205-0
MDL number:
MFCD01738527

Key Documents

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InChI key

HMCCXLBXIJMERM-UHFFFAOYSA-N

InChI

1S/C20H22N4O6S/c1-28-12-17(25)21-16-11-14(31-13-7-5-4-6-8-13)9-10-15(16)22-18(23-19(26)29-2)24-20(27)30-3/h4-11H,12H2,1-3H3,(H,21,25)(H2,22,23,24,26,27)

SMILES string

COCC(=O)Nc1cc(Sc2ccccc2)ccc1\N=C(\NC(=O)OC)NC(=O)OC

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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Application

Febantel may be used as a reference standard in the determination of febantel in samples of animal feed and pharmaceutical formulations, using high performance liquid chromatography (HPLC) and high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS-MS), respectively.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH6743
BCBW3656

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Piyanan Taweethavonsawat et al.
Parasitology research, 106(2), 533-537 (2009-11-17)
Ancylostoma ceylanicum is a common hookworm of dogs, cats and humans in Asia. More recently, this hookworm was found to infect dogs in Australia. The objective of this study was to determine the efficacy of a combination product containing pyrantel
S C Barr et al.
American journal of veterinary research, 59(9), 1134-1136 (1998-09-15)
To evaluate efficacy of a combination of praziquantel, pyrantel pamoate, and febantel at 2 dosages for treating naturally acquired giardiasis in dogs. 6 male and 9 female Beagles. Dogs were identified as naturally infected with Giardia sp, using the zinc
H Mehlhorn et al.
Parasitology research, 90 Suppl 3, S151-S153 (2003-08-21)
Pyrantel embonate and febantel are both constituents of Drontal Plus and Drontal Puppy broad spectrum anthelmintics for dogs. The effects of pyrantel and the febantel metabolite fenbendazole were investigated against Toxocara canis in-vitro by studying changes in worm motility and
Andrea V Scorza et al.
Journal of feline medicine and surgery, 8(1), 7-13 (2005-07-14)
This study evaluated the effect of two combination products containing febantel, pyrantel, and praziquantel (FPP) for the treatment of Giardia species in experimentally infected kittens. In experiment 1, five kittens were administered the United States (US) formulation of FPP at
Patricia A Payne et al.
Journal of the American Veterinary Medical Association, 220(3), 330-333 (2002-02-07)
To determine efficacy of treatment with a combination febantel-praziquantel-pyrantel product, with or without vaccination with a commercial Giardia vaccine, in dogs with naturally occurring giardiasis. Prospective trial. 16 Beagles naturally infected with Giardia duodenalis. During phase 1, 6 dogs were
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