33988
Clopidol
VETRANAL®, analytical standard
Synonym(s):
3,5-Dichloro-2,6-dimethyl-4-pyridinol
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About This Item
Empirical Formula (Hill Notation):
C7H7Cl2NO
CAS Number:
Molecular Weight:
192.04
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cc1nc(C)c(Cl)c(O)c1Cl
InChI
1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)
InChI key
ZDPIZLCVJAAHHR-UHFFFAOYSA-N
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General description
Clopidol belongs to the anticoccidial class of drugs.
Application
Clopidol may be used as a reference standard for the determination of clopidol in:
- Bovine muscle, animal tissues and eggs by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS).
- Environmental water samples by on-line solid phase extraction (SPE) and ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
- Chicken processed foods and muscles by solid-supported liquid extraction (SLE) clean-up and LC-MS/MS.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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G Dusi et al.
Journal of chromatography. A, 882(1-2), 79-84 (2000-07-15)
A rapid and very effective analytical procedure for the simultaneous liquid chromatographic determination of two coccidiostats, clopidol (CLOP) and nicarbazin (NICA), in poultry feeds was developed and tested. The ground feed samples were extracted using aqueous dimethylformamide after moistening with
Miry Blich et al.
The Journal of invasive cardiology, 22(10), 461-464 (2010-10-15)
Traditionally, stent thrombosis (STH) has been regarded as a complication of percutaneous coronary interventions during the first 30 post-procedural days. However, delayed endothelialization associated with the implantation of drug-eluting stents (DES) may extend the risk of thrombosis beyond 30 days.
Analysis of 76 veterinary pharmaceuticals from 13 classes including aminoglycosides in bovine muscle by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Dasenaki ME, et al.
Journal of Chromatography A, 1452(5-6), 67-80 (2016)
L G Ekström et al.
Journal - Association of Official Analytical Chemists, 67(5), 955-957 (1984-09-01)
A method has been developed for the determination of clopidol residues in chicken tissues. After extraction and cleanup, clopidol is esterified in a 2-phase system to clopidol propionate, which is determined by gas chromatography. The 2-phase system includes, in addition
E M Mattern et al.
Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 190(1), 25-30 (1990-01-01)
A fully automated HPLC determination of the coccidiostat meticlorpindol in whole egg, egg white and yolk is described. The sample homogenate is dialysed on-line against water. The dialysate is concentrated on-line on a short reversed-phase (RP) column. The contents of
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