33988
Clopidol
VETRANAL®, analytical standard
Synonym(s):
3,5-Dichloro-2,6-dimethyl-4-pyridinol
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About This Item
Empirical Formula (Hill Notation):
C7H7Cl2NO
CAS Number:
Molecular Weight:
192.04
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
221-008-2
MDL number:
InChI
1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)
InChI key
ZDPIZLCVJAAHHR-UHFFFAOYSA-N
SMILES string
Cc1nc(C)c(Cl)c(O)c1Cl
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
Related Categories
General description
Clopidol belongs to the anticoccidial class of drugs.
Application
Clopidol may be used as a reference standard for the determination of clopidol in:
- Bovine muscle, animal tissues and eggs by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS).
- Environmental water samples by on-line solid phase extraction (SPE) and ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
- Chicken processed foods and muscles by solid-supported liquid extraction (SLE) clean-up and LC-MS/MS.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
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A Arakawa et al.
Veterinary parasitology, 38(1), 55-60 (1991-01-01)
Feed additive anticoccidials currently used in Japan were examined for possible effects on oocyst sporulation of Eimeria tenella. Monensin, salinomycin, lasalocid, amprolium plus ethpabate, amporolium plus ethopabate plus sulfaquinoxaline, clopidol, or nicarbazin were given to chickens continuously via the feed
G F Pang et al.
Journal of AOAC International, 84(5), 1343-1346 (2001-10-17)
A study was made of the distribution and depletion of clopidol residues at different tissue locations in chickens fed with feeds incurred with clopidol. Experiments showed that the residue levels were not identical at 5 different tissue locations in each
G F Pang et al.
Journal of chromatography. A, 882(1-2), 85-88 (2000-07-15)
A high-performance liquid chromatographic-mass spectrometric (HPLC-MS) method has been developed for determination of clopidol residues in chicken tissues. Samples are extracted with acetonitrile. The extracts are cleaned up on an alumina column followed by an anion-exchange column. The clopidol is
R Malisch
Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 184(6), 467-477 (1987-06-01)
Chloramphenicol and meticlorpindol may be determined by HPLC with UV-detection with a limit of 0.02-0.03 mg/kg. Residues of 0.001 mg/kg Chloramphenicol are determined by Capillary-GC with an ECD after an additional clean up step using chromatography on a miniaturized silica
Determination of 18 veterinary antibiotics in environmental water using high-performance liquid chromatography-q-orbitrap combined with on-line solid-phase extraction.
Kim C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1084(5-6), 158-165 (2018)
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