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Clopidol

VETRANAL®, analytical standard

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Synonym(s):
3,5-Dichloro-2,6-dimethyl-4-pyridinol
Empirical Formula (Hill Notation):
C7H7Cl2NO
CAS Number:
2971-90-6
Molecular Weight:
192.04
EC Number:
221-008-2
MDL number:
MFCD00867211
PubChem Substance ID:
329754727
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cc1nc(C)c(Cl)c(O)c1Cl

InChI

1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)

InChI key

ZDPIZLCVJAAHHR-UHFFFAOYSA-N

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General description

Clopidol belongs to the anticoccidial class of drugs.

Application

Clopidol may be used as a reference standard for the determination of clopidol in:
  • Bovine muscle, animal tissues and eggs by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS).
  • Environmental water samples by on-line solid phase extraction (SPE) and ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
  • Chicken processed foods and muscles by solid-supported liquid extraction (SLE) clean-up and LC-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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G Dusi et al.
Journal of chromatography. A, 882(1-2), 79-84 (2000-07-15)
A rapid and very effective analytical procedure for the simultaneous liquid chromatographic determination of two coccidiostats, clopidol (CLOP) and nicarbazin (NICA), in poultry feeds was developed and tested. The ground feed samples were extracted using aqueous dimethylformamide after moistening with
Miry Blich et al.
The Journal of invasive cardiology, 22(10), 461-464 (2010-10-15)
Traditionally, stent thrombosis (STH) has been regarded as a complication of percutaneous coronary interventions during the first 30 post-procedural days. However, delayed endothelialization associated with the implantation of drug-eluting stents (DES) may extend the risk of thrombosis beyond 30 days.
Analysis of 76 veterinary pharmaceuticals from 13 classes including aminoglycosides in bovine muscle by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Dasenaki ME, et al.
Journal of Chromatography A, 1452(5-6), 67-80 (2016)
Determination of 18 veterinary antibiotics in environmental water using high-performance liquid chromatography-q-orbitrap combined with on-line solid-phase extraction.
Kim C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1084(5-6), 158-165 (2018)
L G Ekström et al.
Journal - Association of Official Analytical Chemists, 67(5), 955-957 (1984-09-01)
A method has been developed for the determination of clopidol residues in chicken tissues. After extraction and cleanup, clopidol is esterified in a 2-phase system to clopidol propionate, which is determined by gas chromatography. The 2-phase system includes, in addition
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