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Merck
CN

33989

Cefalexin

VETRANAL®, analytical standard

Synonym(s):

7-(D-α-amino-phenylacetamido)-3-methyl-3-cepheme-4-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C16H17N3O4S
CAS Number:
15686-71-2
Molecular Weight:
347.39
NACRES:
NA.24
PubChem Substance ID:
329754728
UNSPSC Code:
41116107
EC Number:
239-773-6
MDL number:
MFCD00056877

Key Documents

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Product Name

Cefalexin, VETRANAL®, analytical standard

InChI key

ZAIPMKNFIOOWCQ-UEKVPHQBSA-N

InChI

1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1

SMILES string

N[C@@H](C(N[C@@H]1C(N2[C@]1([H])SCC(C)=C2C(O)=O)=O)=O)C3=CC=CC=C3

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

mode of action

cell wall synthesis | interferes

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chemical structure: ß-lactam

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2371
BCCD6883
BCBW7031

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Viviane Jusot et al.
Journal of tropical pediatrics, 60(3), 223-230 (2014-02-18)
Bordetella pertussis still poses an important health threat in developing countries. In Niger, notified pertussis cases are few despite the low diphtheria-tetanus-pertussis/pentavalent vaccine coverage. We aimed to estimate the prevalence of B. pertussis in children aged <5 years consulting at
Steven D Coon et al.
American journal of physiology. Gastrointestinal and liver physiology, 305(10), G678-G684 (2013-09-28)
Glucose-dependent insulinotropic polypeptide (GIP) secreted from jejunal mucosal K cells augments insulin secretion and plays a critical role in the pathogenesis of obesity and Type 2 diabetes mellitus. In recent studies, we have shown GIP directly activates Na-glucose cotransporter-1 (SGLT1)
Adriana Ledezma Estrada et al.
Journal of hazardous materials, 227-228, 41-48 (2012-06-06)
The comparative degradation behavior of cefalexin (CLX) using advanced oxidation processes (AOPs) with the aim of improving CLX biodegradability was studied. Among the AOPs used, RuO(2)/Ti anodic oxidation (AO), AO in the presence of electro-generated H(2)O(2) (AO-H(2)O(2)), and the electro-Fenton
Robert A Silverman et al.
The Pediatric infectious disease journal, 31(8), 872-873 (2012-05-03)
We present a case of severe intertrigo in the neck of a 5-month-old infant. The cause was Streptococcus pyogenes.
P Silley et al.
Journal of dairy science, 95(6), 3448-3453 (2012-05-23)
A combination of kanamycin and cefalexin was licensed in Europe in 2008 to treat bovine clinical mastitis. Preliminary broth and disk clinical breakpoints for this antibiotic combination have been proposed for Staphylococcus aureus, Streptococcus dysgalactiae, Streptococcus uberis, and Escherichia coli.
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