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Merck
CN

33996

Ethopabate

VETRANAL®, analytical standard

Synonym(s):

Methyl 4-acetamido-2-ethoxybenzoate, Ethopabate, Ethyl pabate

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About This Item

Empirical Formula (Hill Notation):
C12H15NO4
CAS Number:
59-06-3
Molecular Weight:
237.25
Beilstein:
2808914
EC Number:
200-414-3
MDL number:
MFCD00075809
UNSPSC Code:
41116107
PubChem Substance ID:
329754735
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCOc1cc(NC(C)=O)ccc1C(=O)OC

InChI

1S/C12H15NO4/c1-4-17-11-7-9(13-8(2)14)5-6-10(11)12(15)16-3/h5-7H,4H2,1-3H3,(H,13,14)

InChI key

GOVWOKSKFSBNGD-UHFFFAOYSA-N

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General description

Ethopabate is an antibiotic used as a coccidiostat in poultry feeds.

Application

Ethopabate may be used as a reference standard in the determination of ethopabate in feed samples using solid phase extraction with high performance liquid chromatography (SPE-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH6715
BCBW4596

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C A Kan et al.
Tijdschrift voor diergeneeskunde, 114(2), 76-82 (1989-01-15)
Amprolium may be used as a coccidiostat in rearing hens and is a therapeutical agent used in laying hens. As a result of cross contamination, low amprolium levels may occur in feed. Feed containing a concentration of amprolium ranging from
The treatment of coccidiosis: studies on the sensitivity of recent field isolates of Eimeria acervulina type to anticoccidial drugs given in the drinking water.
H D Chapman
Journal of comparative pathology, 92(2), 213-218 (1982-04-01)
H D Chapman
Research in veterinary science, 46(3), 419-420 (1989-05-01)
Treatment with toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate prevented mortality in chickens infected with field isolates of Eimeria tenella. Amprolium/ethopabate was the most effective drug in reducing lesions caused by the parasites. Few oocysts of E tenella were produced in birds medicated
Illegal use of Amprol-Plus for game.
O Swarbrick
The Veterinary record, 127(12), 315-315 (1990-09-22)
T Nagata et al.
Journal - Association of Official Analytical Chemists, 68(1), 27-28 (1985-01-01)
A liquid chromatographic (LC) method is described for determination of ethopabate residues in chicken tissues. The drug is extracted from tissues with acetonitrile, and the extract is concentrated to 2-3 mL. This aqueous solution is rinsed with ethyl acetate and
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