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Merck
CN

34000

Toltrazuril

VETRANAL®, analytical standard

Synonym(s):

1-Methyl-3-{3-methyl-4-[4-(trifluoromethylthio)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione, Baycox

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About This Item

Empirical Formula (Hill Notation):
C18H14F3N3O4S
CAS Number:
69004-03-1
Molecular Weight:
425.38
NACRES:
NA.24
PubChem Substance ID:
329754744
UNSPSC Code:
41116107
MDL number:
MFCD00867201

Key Documents

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Product Name

Toltrazuril, VETRANAL®, analytical standard

InChI

1S/C18H14F3N3O4S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)28-12-4-6-13(7-5-12)29-18(19,20)21/h3-9H,1-2H3,(H,22,25,26)

SMILES string

CN1C(=O)NC(=O)N(C1=O)c2ccc(Oc3ccc(SC(F)(F)F)cc3)c(C)c2

InChI key

OCINXEZVIIVXFU-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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Related Categories

Application

Toltrazuril may be used as a reference standard in the determination of toltrazuril in pork using high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Toltrazuril is found to be highly effective against coccidia and is used in controlling coccidiosis.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Environment
GHS09

signalword

Warning

hcodes

H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8112
BCCF1934
BCBZ3479
BCBV1965

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S Cériac et al.
BMC veterinary research, 13(1), 326-326 (2017-11-11)
Gastrointestinal nematode (GIN) remains the most important pathogenic constraint of small ruminant production worldwide. The improvement of the host immune response against GIN though breeding for improved animal resistance, vaccination and nutritional supplementation appear as very promising methods. The objective
Pd-catalyzed synthesis of Ar-SCF3 compounds under mild conditions.
Georgiy Teverovskiy et al.
Angewandte Chemie (International ed. in English), 50(32), 7312-7314 (2011-06-22)
S Cériac et al.
Scientific reports, 9(1), 1237-1237 (2019-02-06)
Resistance to gastro-intestinal nematode (GIN) in small ruminant is expected to arise from protein-rich rather than from energy-rich feeds. The objective of this study was to investigate the effect of the quality of the dietary proteins on the response of
Aruna Shrestha et al.
Frontiers in microbiology, 11, 983-983 (2020-06-09)
The protozoan parasite Cystoisospora suis causes diarrhea and reduced weight gain in suckling piglets. Infections occur in the first days of life; it is transient but can lead to dysbiosis, exacerbating disease and increasing mortality. Cystoisosporosis is effectively controlled by
Toltrazuril effective against a broad spectrum of protozoan parasites
Mehlhorn H, et al.
Parasitology Research, 75(1), 64-66 (1988)
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