34003
HMMNI
VETRANAL®, analytical standard
Synonym(s):
2-Hydroxymethyl-1-methyl-5-nitro-1H-imidazole
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About This Item
Empirical Formula (Hill Notation):
C5H7N3O3
CAS Number:
Molecular Weight:
157.13
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
213-312-9
MDL number:
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cn1c(CO)ncc1[N+]([O-])=O
InChI
1S/C5H7N3O3/c1-7-4(3-9)6-2-5(7)8(10)11/h2,9H,3H2,1H3
InChI key
JSAQDPJIVQMBAY-UHFFFAOYSA-N
General description
HMMNI is a major metabolite of nitroimidazole drug, dimetridazole (DMZ).
HMMNI is a hydroxy metabolite of nitroimidazole antibiotics, belonging to a class of veterinary drugs with therapeutic applications in the treatment and prevention of certain bacterial and protozoal diseases in poultry and swine.
Application
HMMNI may be used as an analytical reference standard for the determination of the analyte in:
- Different matrices of swine using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) and ultra-performance liquid chromatography coupled to electrospray tandem mass spectrometry (UPLC-ESI-MS/MS).
- Biological & environmental matrices using liquid chromatography with ultraviolet detection (LC-UV).
HMMNI may be used as a reference standard for the determination of HMMNI in porcine liver using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Muta. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
flash_point_f
Not applicable
flash_point_c
Not applicable
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Determination of 5-nitroimidazoles and corresponding hydroxy metabolites in swine kidney by ultra-performance liquid chromatography coupled to electrospray tandem mass spectrometry.
Xia Xi, et al.
Analytica Chimica Acta, 637(1-2), 79-86 (2009)
Analytical methodologies for the determination of nitroimidazole residues in biological and environmental liquid samples: a review.
Mahugo-Santana C, et al.
Analytica Chimica Acta, 665(2), 113-122 (2010)
Maykel Hernández-Mesa et al.
Food chemistry, 252, 294-302 (2018-02-27)
A novel multiresidue method is proposed for the determination of 12 5-nitroimidazoles and their metabolites in fish roe samples using UHPLC-MS/MS. A salting-out assisted liquid-liquid extraction procedure was performed prior to sample analysis. The separation of compounds was accomplished using
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 34003-10MG-R | 04061826752807 |