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Merck
CN

34057

Diclazuril

VETRANAL®, analytical standard

Synonym(s):

2,6-Dichloro-α-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile

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About This Item

Empirical Formula (Hill Notation):
C17H9Cl3N4O2
CAS Number:
101831-37-2
Molecular Weight:
407.64
NACRES:
NA.24
PubChem Substance ID:
329754784
UNSPSC Code:
41116107
MDL number:
MFCD00867203

Key Documents

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Product Name

Diclazuril, VETRANAL®, analytical standard

InChI

1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)

SMILES string

Clc1ccc(cc1)C(C#N)c2c(Cl)cc(cc2Cl)N3N=CC(=O)NC3=O

InChI key

ZSZFUDFOPOMEET-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Repr. 2 - STOT RE 2

target_organs

Lungs,Liver,lymph node

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ8995
BCCC1851
BCBS6752V
BCBR9163V

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Bian-hua Zhou et al.
Parasitology research, 111(4), 1447-1455 (2012-07-04)
The receptor for activated C kinase (RACK) cDNA of second-generation merozoites of Eimeria tenella was cloned using reverse transcriptase polymerase chain reaction and rapid amplification of cDNA ends, compared with other species, and then successfully expressed using the pET-28a vector
Bian-hua Zhou et al.
Experimental parasitology, 125(3), 264-270 (2010-02-09)
The effects of diclazuril on mRNA expression levels of invasion-related microneme genes were examined in second-generation merozoites of Eimeria tenella (E. tenella) by quantitative real-time (QRT) PCR. Diclazruil treatment of infected chickens significantly decreased the number of second-generation merozoites by
Bianhua Zhou et al.
Veterinary parasitology, 168(3-4), 217-222 (2009-12-17)
Diclazuril, a benzeneacetonitrile anticoccidial agent, has potent activity against various stages of Eimeria tenella (E. tenella). To study the effects of diclazuril on E. tenella merozoites, purified second-generation merozoites were obtained from infected chicken caecal tissue at 120h after inoculation
Antonio Ruiz et al.
Parasitology research, 110(6), 2131-2136 (2011-12-24)
Coccidiosis is probably the main parasitic disease affecting goat kids around the weaning period, leading to high economic losses in goat production due to deaths and delayed growth rates of infected animals. A total of 101 kids of 2-4 weeks
Assessing the effect of diclazuril on the intestinal absorptive capacity of broilers infected with experimental coccidiosis, using d-xylose absorption test.
H Nodeh et al.
Journal of veterinary pharmacology and therapeutics, 31(3), 265-267 (2008-05-13)
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