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Merck
CN

34078

Oxyclozanide

VETRANAL®, analytical standard

Synonym(s):

2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide, 3,3′,5,5′,6-Pentachloro-2′-hydroxysalicylanilide

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About This Item

Empirical Formula (Hill Notation):
C13H6Cl5NO3
CAS Number:
2277-92-1
Molecular Weight:
401.46
NACRES:
NA.24
PubChem Substance ID:
329754798
UNSPSC Code:
41116107
EC Number:
218-904-0
MDL number:
MFCD00864507

Key Documents

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Product Name

Oxyclozanide, VETRANAL®, analytical standard

InChI key

JYWIYHUXVMAGLG-UHFFFAOYSA-N

InChI

1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)

SMILES string

Oc1c(Cl)cc(Cl)cc1NC(=O)c2c(O)c(Cl)cc(Cl)c2Cl

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Oxyclozanide is an anthelmintic agent, which can show activity against Fasciola hepatica, a parasitic trematode and hence, can be used in the treatment of liver fluke infections.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5895
BCCK0517
BCCJ3689
BCCD2132
BCCC1795

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Treatment of Dicrocoelium dendriticum with a combination of thiophanate and brotianide.
B Tinar et al.
The Veterinary record, 123(25), 650-651 (1988-12-17)
E E Guobadia et al.
Veterinary parasitology, 68(3), 269-282 (1997-02-01)
The 17kDa and 69kDa polypeptide antigens which are specific to Fasciola gigantica were excised from polyacrylamide gels and used for the immunization of rabbits to raise monospecific antisera against these polypeptides. These sera were labelled with horseradish peroxidase and used
C Paraud et al.
Veterinary journal (London, England : 1997), 180(2), 265-267 (2008-03-04)
Paramphistome infections are very common in ruminants and may induce clinical signs, but little is known about effective treatments. In this study, the efficacy of oxyclozanide against Calicophoron daubneyi was studied in goats and its activity tested against immature stages
S A Spence et al.
Australian veterinary journal, 69(9), 217-220 (1992-09-01)
A significant increase in milk production, averaging 164 litres per cow per lactation (a 4.8% increase), was seen after cows infected with gastrointestinal nematodes, paramphistomes and Fasciola hepatica were treated with broad-spectrum anthelmintics. Three hundred and ninety pairs of cows
O Hindsbo et al.
International journal for parasitology, 26(11), 1287-1294 (1996-11-01)
After infection with the intestinal helminths Moniliformis moniliformis or Nippostrongylus brasiliensis, worm-specific IgE first appeared in the serum rats between days 10 and 24 p.i., varying with host age, worm species and worm dose used. The rate of increase in
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