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Merck
CN

34142

Fumonisin B2 solution

~50 μg/mL in acetonitrile: water (50:50), analytical standard

Synonym(s):

FB2

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About This Item

Empirical Formula (Hill Notation):
C34H59NO14
CAS Number:
116355-84-1
Molecular Weight:
705.83
MDL number:
MFCD32197368
UNSPSC Code:
85151701
PubChem Substance ID:
24860941
NACRES:
NA.24

Key Documents

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Product Name

Fumonisin B2 solution, ~50 μg/mL in acetonitrile: water (50:50), analytical standard

SMILES string

CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)[C@H](C[C@@H](C)CCCCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O

InChI

1S/C34H59NO14/c1-5-6-12-21(3)32(49-31(43)18-24(34(46)47)16-29(40)41)27(48-30(42)17-23(33(44)45)15-28(38)39)14-20(2)11-9-7-8-10-13-25(36)19-26(37)22(4)35/h20-27,32,36-37H,5-19,35H2,1-4H3,(H,38,39)(H,40,41)(H,44,45)(H,46,47)

InChI key

UXDPXZQHTDAXOZ-UHFFFAOYSA-N

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

~50 μg/mL in acetonitrile: water (50:50)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

Quality Level

100

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Analysis Note

purity : ≥94.0% (HPLC)

Application

Fumosin B2 maybe used to study the effect of temperatures from ambient to 150°C and solvent compositions (methanol-water, acetonitrile-methanol-water, ethanol-water, and 100% water) on recovery of fumonisins from corn products.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Certan Vial
Fumonisin B2 belongs to the family of toxins known as fumonisins. It is produced by several species of Fusarium molds primarily by Fusarium verticillioide. It is one of the major mycotoxin contaminant in corn and corn-based foods. Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than the latter and it inhibits sphinganine-N-acetyltransferase (ceramide synthase).
Fumonisin B2 is a carcinogenic mycotoxin generally present on corn based food and feed-stuff, which is produced by the fungus Fusarium verticillioides and Fusarium moniliforme. Fumonisin B2 can also be detected in the industrially important fungi, Aspergillus niger.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

flash_point_f

35.6 °F

flash_point_c

2 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

高风险级别生物产品--毒素类产品
危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6997
BCCN1086
BCCL9183
BCCL1412
BCCK7503

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Biomarkers in Toxicology.
Gupta RC.
Science, 555-556 (2014)
Occurrence of fumonisins B1 and B2 in corn-based products from the Swiss market
Pittet A, et al.
Journal of Agricultural and Food Chemistry, 40, 1352-1354 (1992)
Fumonisin B2 production by Aspergillus niger
Frisvad.AJ, et al.
Journal of Agricultural and Food Chemistry, 55, 9727-9732 (2007)
J F Lawrence et al.
Journal of AOAC International, 83(3), 604-611 (2000-06-27)
Fumonisins B1 and B2 were extracted from naturally contaminated corn products by using different extraction solvent compositions (methanol-water, acetonitrile-methanol-water, ethanol-water, and 100% water) and a range of temperatures from ambient to 150 degrees C. Ground samples of several corn products
Jesper Mølgaard Mogensen et al.
Journal of industrial microbiology & biotechnology, 38(9), 1329-1335 (2010-12-07)
Tolypocladium inflatum is known primarily for its production of the cyclosporines that are used as an immunosuppressive drug. However, we report here the production of the carcinogenic fumonisins B(2) and B(4) by this biotechnologically relevant fungal genus. These mycotoxins were
View All Related Papers

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