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34176

Oxfendazole

VETRANAL®, analytical standard

Synonym(s):

Methyl 5-(phenylsulfinyl)-benzimidazol-2-carbamate

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About This Item

Empirical Formula (Hill Notation):
C15H13N3O3S
CAS Number:
53716-50-0
Molecular Weight:
315.35
NACRES:
NA.24
PubChem Substance ID:
329754866
UNSPSC Code:
41116107
EC Number:
258-714-5
MDL number:
MFCD00801063
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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)S(=O)c3ccccc3

InChI

1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChI key

BEZZFPOZAYTVHN-UHFFFAOYSA-N

General description

Oxfendazole is a benzimidazole anthelmintic drug, effective against cysticercosis, echinococcosis and fasciolosis.
Oxfendazole is a member of benzimidazole group of anthelmintics.

Application

Oxfendazole may be used as an analytical reference standard for the determination of the analyte in bovine liver by liquid chromatography method.
Oxfendazole may be used as a reference standard in the determination of oxfendazole in pharmaceutical preparations using reversed-phase high-performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL3268
BCCG5828
BCCB2008
BCCB2006
BCBT4620

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Yasuaki Dewa et al.
Archives of toxicology, 81(9), 647-654 (2007-03-07)
The effect of oxfendazole (OX), a benzimidazole anthelmintic, on hepatic gene expression was investigated in the liver of rats as a preliminary study to elucidate the possible mechanism of its non-genotoxic hepatocarcinogenesis. The liver from a male F344/N rat given
Jihei Nishimura et al.
Archives of toxicology, 84(2), 143-153 (2009-12-25)
To clarify whether enzymatically modified isoquercitrin (EMIQ) or melatonin (MLT) supplementation reduces oxidative stress-mediated hepatocellular tumor-promoting effect of oxfendazole (OX), a benzimidazole anthelmintic, male rats were administered a single intraperitoneal injection of N-diethylnitrosamine (DEN) and were fed a diet containing
Chemotherapy of Gastrointestinal Helminths.
Handbook of Experimental Pharmacology, 77, 111-114 (2012)
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Global Trade Item Number

SKUGTIN
34176-100MG04061826754498