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Merck
CN

34198

Ractopamine hydrochloride

VETRANAL®, analytical standard

Synonym(s):

4-{3-[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]aminobutylphenol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C18H23NO3 · HCl
CAS Number:
90274-24-1
Molecular Weight:
337.84
NACRES:
NA.24
PubChem Substance ID:
329754886
UNSPSC Code:
41116107
EC Number:
415-170-5
MDL number:
MFCD07781271

Key Documents

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InChI key

JHGSLSLUFMZUMK-UHFFFAOYSA-N

InChI

1S/C18H23NO3.ClH/c1-13(2-3-14-4-8-16(20)9-5-14)19-12-18(22)15-6-10-17(21)11-7-15;/h4-11,13,18-22H,2-3,12H2,1H3;1H

SMILES string

OC1=CC=C(C(O)CNC(C)CCC2=CC=C(O)C=C2)C=C1.Cl

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable, solid phase extraction (SPE): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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General description

Ractopamine hydrochloride is a phenethanolamine β-adrenergic agonist (β-AA) that improves growth performance and affects carcass characteristics in livestock, through increased protein synthesis. Ractopamine hydrochloride is FDA approved animal feed additive used in some third countries like the USA, Canada, Japan, and Mexico for the growth promotion in fattening of pigs and cattle. In the USA, Ractopamine hydrochloride is authorized for use in pigs and cattle at a feed concentration of 5-20 mg kg-1 for finishing pigs and 10-30 mg kg-1 for cattle in confinement.

Application

The analytical standard can be used to:
  • Evaluate the comparative effects of ractopamine hydrochloride and zilpaterol hydrochloride on growth performance, carcass traits, and longissimus tenderness of finishing beef steers
  • Determine the effects of ractopamine hydrochloride on growth performance, carcass characteristics, physiological response to handling, and mobility during shipment for slaughter
  • Evaluate the effect of ractopamine hydrochloride on growth performance, carcass cutting yield, and processing characteristics of boneless hams and bellies from finishing pigs
  • Study the effects of ractopamine hydrochloride and zilpaterol hydrochloride on growth, diet digestibility, intake, and carcass characteristics of feedlot lambs
  • Evaluate the effects of ractopamine hydrochloride on growth performance, feed intake patterns, and acid-base balance in feedlot cattle

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7494
BCCG1332
BCBT4623

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C S Abney et al.
Journal of animal science, 85(11), 3090-3098 (2007-07-05)
Two experiments evaluated effects of ractopamine hydrochloride (RAC) on performance, intake patterns, and acid-base balance of feedlot cattle. In Exp. 1, 360 crossbred steers (Brangus, British, and British x Continental breeding; initial BW = 545 kg) were used in a
J A Hagenmaier et al.
Journal of animal science, 95(5), 1977-1992 (2017-07-21)
Feedlot cattle ( = 128; BW = 549 ± 60 kg) were used to evaluate the effects of ractopamine hydrochloride (RAC) on growth performance, physiological response to handling, and mobility during shipment for slaughter in a study utilizing a split-plot
L E Watkins et al.
Journal of animal science, 68(11), 3588-3595 (1990-11-01)
Six trials involving 888 pigs (Study 1) and three trials involving 360 pigs (Study 2) were conducted at various geographical locations in the U.S. and Canada to evaluate the effect of ractopamine hydrochloride on the performance and carcass characteristics of
Effect of ractopamine hydrochloride and zilpaterol hydrochloride on growth, diet digestibility, intake and carcass characteristics of feedlot lambs
Lopez-Carlos MA, et al.
Livestock Science, 23-30 null
C R Stites et al.
Journal of animal science, 69(8), 3094-3101 (1991-08-01)
This study was designed to evaluate growth performance, carcass cutting yield, and processing characteristics of boneless hams and bellies from finishing pigs fed diets containing 0, 5, 10, or 20 ppm of the phenethanolamine ractopamine hydrochloride (RAC). Sixty pigs were
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