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Merck
CN

36182

Oryzalin

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12H18N4O6S
CAS Number:
19044-88-3
Molecular Weight:
346.36
EC Number:
242-777-0
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329755324
Beilstein/REAXYS Number:
2177305
MDL number:
MFCD00078725

Key Documents

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InChI key

UNAHYJYOSSSJHH-UHFFFAOYSA-N

InChI

1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)

SMILES string

CCCN(CCC)c1c(cc(cc1[N+]([O-])=O)S(N)(=O)=O)[N+]([O-])=O

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Quality Level

100

Related Categories

General description

Oryzalin is a dinitroaniline herbicide, which can have the tendency to inhibit spindle formation and thereby lead to choromosome doubling in vitro in the diploid hybrid of Rosa rugosa. It can also serve as a potent antiparasitic therapeutic candidate, in the treatment of leishmaniasis disease.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Skin Sens. 1 - STOT RE 2

target_organs

Blood,Kidney

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Information

农药列管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8114
BCCG0802
BCCB2195
BCBZ8664

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Chromosome doubling in a Rosa rugosa Thunb. hybrid by exposure of in vitro nodes to oryzalin: the effects of node length, oryzalin concentration and exposure time
Allum.F.J, et al.
Plant Cell Reports, 26(11), 1977-1984 (2007)
Andrew Muroyama et al.
Current biology : CB, 30(22), 4467-4475 (2020-09-19)
Multicellular development depends on generating and precisely positioning distinct cell types within tissues. During leaf development, pores in the epidermis called stomata are spaced at least one cell apart for optimal gas exchange. This pattern is primarily driven by iterative
Rapid and reversible high-affinity binding of the dinitroaniline herbicide oryzalin to tubulin from Zea mays L
Hugdahl.DJ and Morejohn.CL
Plant Physiology, 102(3), 725-740 (1993)
Rui M Lopes et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(2), 281-290 (2012-07-10)
Oryzalin (ORZ) is a dinitroaniline that has attracted increasing interest for the treatment of leishmaniasis. The possible use of ORZ as an antiparasitic agent is limited by low water solubility associated with an in vivo rapid clearance. The aim of
Jelmer J Lindeboom et al.
Plant physiology, 161(3), 1189-1201 (2013-01-10)
The ordered arrangement of cortical microtubules in growing plant cells is essential for anisotropic cell expansion and, hence, for plant morphogenesis. These arrays are dismantled when the microtubule cytoskeleton is rearranged during mitosis and reassembled following completion of cytokinesis. The
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