Skip to Content
Merck
CN

Key Documents

View All Documentation

37018

Tenuazonic acid

analytical standard

Synonym(s):

(5S)-3-Acetyl-1,5-dihydro-4-hydroxy-5-[(1S)-1-methylpropyl]-2H-pyrrol-2-one, (S)-3-Acetyl-5-(S)-sec-butyltetramic acid, (S)-3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C10H15NO3
CAS Number:
610-88-8
Molecular Weight:
197.23
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329755583
MDL number:
MFCD00242648
Beilstein/REAXYS Number:
3589518
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@@H]1NC(=O)C(C(C)=O)=C1O

InChI

1S/C10H15NO3/c1-4-5(2)8-9(13)7(6(3)12)10(14)11-8/h5,8,13H,4H2,1-3H3,(H,11,14)/t5-,8-/m0/s1

InChI key

CEIZFXOZIQNICU-XNCJUZBTSA-N

General description

Tenuazonic acid is a mycotoxin, which belongs to the class of tetramic acids, the largest family of natural products. It is generally isolated from phytopathogenic fungal species like Alternaria alternata, A. longipes and A. tenuissima.
Tenuazonic acid is a biologically active compound and its mode of action involves the inhibition of protein biosynthesis.

Application

Tenuazonic acid may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Cornflakes using high-performance liquid chromatography (HPLC) technique.
  • Human urine samples using isotope dilution assay method and liquid chromatography coupled to a hybrid triple quadrupole/linear ion trap mass spectrometer.
  • Cereals using high-performance liquid chromatography–electrospray ionization ion-trap multistage mass spectrometry (HPLC- ESI ion-trap (IT) MS2). ESI Fourier transform-ion cyclotron resonance tandem mass spectrometry (FTICR-MS2) technique is used for product characterization, post derivatization with 2,4-dinitrophenylhydrazine.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Preparation Note

Dried down, ~100 μg/mL after reconstitution with 1 mL of water

Analysis Note

purity : ≥96.0% (HPLC)

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

农药列管产品
高风险级别生物产品--毒素类产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN4448
BCCM9525
BCCM6454
BCCM5000
BCCL2078

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Simultaneous determination of ochratoxin A and cyclopiazonic, mycophenolic, and tenuazonic acids in cornflakes by solid-phase microextraction coupled to high-performance liquid chromatography
Aresta A, et al.
Journal of Agricultural and Food Chemistry, 51(18), 5232-5237 (2003)
Recent advances in tenuazonic acid as a potential herbicide
Chen S and Qiang S
Pesticide Biochemistry and Physiology (2017)
Determination of tenuazonic acid in human urine by means of a stable isotope dilution assay
Asam S, et al.
Analytical and Bioanalytical Chemistry, 405(12), 4149-4158 (2013)
View All Related Papers

Global Trade Item Number

SKUGTIN
37018-0.1MG04061831833409